How to Identify Diabetes-related Traits?

Type 2 diabetes might be linked to genetics due to mutations in any gene involved in controlling glucose levels so it is important to identify these glycaemic traits.

A largescale genetic study by the University of Exeter along with Magic collaboration made up of more than 400 global academics conducted a genomic research in Europeans and published in the journal Nature Genetics.

‘Genetic variation according to ancestry impacts diabetes diagnosis.’

The team analyses data of glycaemic traits used for diabetes diagnosis in the blood including individuals of East Asian, Hispanic, African-American, South Asian and sub-Saharan African origin make them to discover 24 more loci - or regions of the genome -linked to glycaemic traits.

Professor In�s Barroso, of the University of Exeter, who led the research, said: "Type 2 diabetes is an increasingly huge global health challenge- with most of the biggest increases occurring outside of Europe. While there are a lot of shared genetic factors between different countries and cultures, our research tells us that they do differ, in ways that we need to understand. It's critical to ensuring we can deliver a precision diabetes medicine approach that optimises treatment and care for everyone".

Though some loci were not detected in all ancestries they were useful to capture information about the glycaemic trait in that ancestry is an important finding of the study to deliver a precision diabetes medicine approach optimizes treatment and care for everyone.



Source: Medindia