Clofibrate - Drug Information

Generic Name : Clofibrate
Pronunciation : kloe FIB rate

ICD Code : | Therapeutic Classification : Fibrate Drug

Trade Name(s) :

International - Atromid- S.

Why is Clofibrate Prescribed? (Indications)

This medication is a dyslipidaemic agent, prescribed for hyperlipidaemia. It lowers triglycerides and very-low-density lipoprotein (VLDL) level.

When should Clofibrate not to be taken? (Contraindications)

Contraindicated in patients with known hypersensitivity, severe liver or kidney impairment, cirrhosis, during pregnancy and breastfeeding.

What is the dosage of Clofibrate?

Initial: PO- The recommended dosage for adults is 2 g daily in divided doses.

How should Clofibrate be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Clofibrate?

* Caution should be exercised in patients with history of peptic ulcer, underactive thyroid gland, diabetes, and who are taking other medications.
* Follow diet and exercise program regularly as directed by your physician.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Clofibrate?

Most Common - Nausea.
Gastrointestinal - Vomiting, loose stools, indigestion, flatulence, stomach inflammation and abdominal distress.
Central Nervous System - Headache, dizziness, and fatigue.
Musculoskeletal - Muscle cramping, aching and weakness.
Skin - Skin rash, hives, itching, dry brittle hair and hair loss.
Heart - Chest pain, abnormal heart rhythm, and vein inflammation.
Blood - Decrease in white blood cells, anemia and eosinophilia.
Miscellaneous - Weight gain.

What are the other precautions for Clofibrate?

* Avoid excess dosage.

What are the storage conditions for Clofibrate?

Store it at room temperature (25�C).

Schedule H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.