Information on genetic risks is rarely definite and in medical genetics the
risks are estimated almost entirely in terms of ‘probabilities or odds’.
This is the form of risk estimate available for most of the more common non –
mendelian or chromosomal disorders. This varies between population and changes
These risk estimates can be given only when a clean basis of single gene
inheritance can be recognized for a disorder.
This is the most satisfactory form of risk estimate because they allow a clean
differentiation into categories of negligible risk.Mendelian Modes of inheritance:AUTOSOMAL RECESSIVE INHERITANCE
Example of above type of Autosomal Recessive Inheritance includes the following:
- infantile polycystic kidney
- Zellwegar syndrome