Estimation of Risks of Genetic Counselling
This is the form of risk estimate available for most of the more common non – mendelian or chromosomal disorders. This varies between population and changes with time.
These risk estimates can be given only when a clean basis of single gene inheritance can be recognized for a disorder.
This is the most satisfactory form of risk estimate because they allow a clean differentiation into categories of negligible risk.
Mendelian Modes of inheritance:
Example of above type of Autosomal Recessive Inheritance includes the following:
- infantile polycystic kidney disease
- Zellwegar syndrome