Reducing Tumor-associated Immune Cell Protein Decreases Tumor Progression

by Bidita Debnath on  July 9, 2013 at 6:10 PM Cancer News
RSS Email Print This Page Comment
In cancer patients, the number of tumor-associated immune cells is correlated with poor prognosis.
 Reducing Tumor-associated Immune Cell Protein Decreases Tumor Progression
Reducing Tumor-associated Immune Cell Protein Decreases Tumor Progression
Advertisement

Reducing these cells in mouse models of breast cancer reduces tumor metastasis, indicating that tumor-immune interactions are critical for cancer progression. In this issue of the Journal of Clinical Investigation, Shelley Earp and colleagues at the University of North Carolina a Chapel Hill demonstrate that removal of the protein MerTK from immune cells decreased tumor growth in mouse models of breast cancer, melanoma, and colon cancer.

Advertisement
Loss of MerTK reduced the release of molecules associated with inflammation. These findings suggest that drugs that inhibit MerTK may stimulate anti-tumor responses and could potentially have clinical benefit.

Source: Eurekalert
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Parkinsons Disease Surgical Treatment Tumor Markers For Cancer Diagnosis and Prognosis Myasthenia Gravis Magical Millets for Your Health The Basics of Baby Food Diet and Nutrition Tips for Athletes Nutrition IQ 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive