Fusobacteria Use Sugar-Binding Protein to Develop Colon Cancer

by Bidita Debnath on  August 11, 2016 at 2:05 AM Cancer News
RSS Email Print This Page Comment
Bacteria called fusobacteria, commonly found in the mouth, use a sugar-binding protein to stick to develop colorectal polyps and cancers, suggests a new study by researchers from Harvard T.H. Chan School of Public Health and Hebrew University-Hadassah School of Dental Medicine.
 Fusobacteria Use Sugar-Binding Protein to Develop Colon Cancer
Fusobacteria Use Sugar-Binding Protein to Develop Colon Cancer
Advertisement

While certain fusobacteria have previously been shown to worsen colorectal cancer in animals by the Garrett Lab at Harvard Chan School, this study is the first to demonstrate how they may get to and stick to developing tumors.

Advertisement
Understanding this mechanism is an important step toward fighting colorectal cancer, said co-senior study author Wendy Garrett, Melvin J. and Geraldine L. Glimcher Associate Professor of Immunology and Infectious Diseases at Harvard Chan School.

It might inform ways of blocking fusobacteria from homing in on colorectal tumors, she said. "Alternatively, and perhaps more importantly, our findings suggest that drugs targeting the same or similar mechanisms of bacterial sugar-binding proteins could potentially prevent these bacteria from exacerbating colorectal cancer."

The study will be published online in Cell Host & Microbe. Colorectal cancer is the third leading cause of cancer-related deaths in the United States, and microbes have emerged as key factors that influence the development and progression of the disease.

Garrett and co-senior study author Gilad Bachrach of Hebrew University used human samples and mouse models to confirm their new findings on fusobacteria.

Source: Medindia
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Cancer and Homeopathy Colo-rectal cancer - Management Colorectal Cancer Cancer Facts Cancer Tattoos A Body Art Colon Crohns Disease Magical Millets for Your Health Diverticulosis and Diverticulitis 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive