A panel of lung tumours from a population exposed to arsenic has been examined by researchers from the British Columbia Cancer Research Center.
Arsenic contaminated water is a global threat, currently affecting more than 100 million people. Both genetic and epigenetic changes drive arsenic-induced carcinogenesis and lung cancer is one of the main consequences of this process.
"Lung tumours induced by arsenic are different molecular entities and specific therapeutic approaches should be considered," said Victor Martinez, researcher at the British Columba Cancer Research Center.
"These results may help to prevent arsenic-related cancer in other parts of the world, such as USA and Canada, where exposure to arsenic (even at low levels) has been also linked with lung cancer and other diseases," he noted.
Martinez will share his latest research at the 5th Latin American Conference on Lung Cancer.