Maternal Diet can Impact Asthma Risk in Offspring

by VR Sreeraman on  September 20, 2008 at 12:21 PM Diet & Nutrition News
RSS Email Print This Page Comment bookmark
Font : A-A+

 Maternal Diet can Impact Asthma Risk in Offspring
A maternal diet rich in methyl donors, of which one source is the prenatal supplement folate, can increase developing fetus' chances of suffering from asthma after birth.

John Hollingsworth and colleagues, at Duke University Medical Center, Durham, have generated the evidence in mice.

In the study, the development and severity of allergic airway disease (the experimental equivalent of asthma) was found to be enhanced in mice born to mothers who had eaten a diet supplemented with methyl donors.

In addition, enhanced development and severity of allergic airway disease was observed in mice born to those exposed to methyl donors in utero, i.e. the problems were inherited.

Further analysis indicated that some genes in the mice exposed to methyl donors in utero were modified by methylation in a different way to mice not exposed to methyl donors in utero.

This change in the pattern of methylation, altered the expression of the genes and is likely to be the underlying cause of the increased development and severity of allergic airway disease.

Both the authors and, in an accompanying commentary, Rachel Miller, at

Columbia University College of Physicians and Surgeons, New York, discuss the potential implications of this study in light of the fact that folate is a source of methyl donors and is an important prenatal supplement that helps prevent congential abnormalities.

As they caution, it is important to determine if the same effects occur in humans before changing the current recommendations about prenatal supplementation.

Source: ANI
LIN

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Childhood Asthma Diet Pills Asthma Low Carbohydrate Diet Atkins Diet The Cabbage Diet South Beach Diet Negative Calorie Diet Bulimia Nervosa Why Do We Eat - Nutrition Facts 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...