A man-made fat called Intralipid, which is currently used as a component of intravenous nutrition and to treat rare overdoses of local anesthetics, may also offer protection for patients suffering from heart attacks.
A UCLA preclinical study identified how Intralipid - a fat emulsion made up of a combination of soy bean oil, egg phospholipids and glycerin that provides essential fatty acids - can prevent extensive heart damage and help preserve heart function when used during the return of blood flow to the heart immediately following a heart attack.
The research has shown that intralipid may help cell integrity and function when the body is under stress, such as during a heart attack, thus introducing a new way to significantly decrease damage to the heart muscle due to reperfusion injury or to prolong the tolerance of a tissue or an organ to lack of oxygen.
The findings may have implications for future therapies. The technique is not limited to the heart, researchers said, and could potentially be used for any ischemic organs suffering a blockage in blood flow or for organs used for transplant.