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Human Nose Too Cold For Bird Flu Viruses To Thrive: Study
The researchers say that the new finding may help explain why bird flu viruses do not cause pandemics in humans easily.
In their study report, the scientists point out that there are 16 subtypes of avian influenza, some of which can mutate into forms that can infect humans by swapping proteins on their surface with proteins from human influenza viruses.
They say that normal avian influenza viruses do not spread extensively in cells at 32 degrees Celsius, the temperature inside the human nose, which is probably because the viruses usually infect the guts of birds, which are warmer, at 40 degrees Celsius.
Based on this observation, according to them, it may be said that avian flu viruses that have not mutated are less likely to infect people, as the first site of infection in humans is usually the nose.
When the researchers created a mutated human influenza virus by adding a protein from the surface of an avian influenza virus, they found it to struggle to thrive at 32 degrees Celsius. This indicates that any mutated virus would have to undergo further changes to adapt to the conditions in the human body.
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