HRT Raises Breast Cancer Recurrence Risk in Survivors

by VR Sreeraman on  March 26, 2008 at 6:03 PM Cancer News
RSS Email Print This Page Comment
HRT Raises Breast Cancer Recurrence Risk in Survivors
Hormone replacement therapy (HRT) increases the risk of disease recurrence in breast cancer survivors, warns a new study.
Advertisement

Previous studies have shown that HRT increases breast cancer incidence in peri- and postmenopausal healthy women, but its impact on breast cancer survivors has remained obscure.

Advertisement
Now, the study by Lars Holmberg, M.D., Ph.D., currently at King's College London and his mostly Scandinavian colleagues, has warned that survivors who took HRT were more likely to suffer disease recurrence than those who did not take HRT.

As a part of their study the researchers analysed breast cancer rates for 221 women in the randomized HABITS (Hormonal Replacement After Breast Cancer -Is It Safe?) trial after a median follow-up of four years.

At the time of this analysis, the researchers found that 17.6 percent or 39 women in the HRT treatment arm had developed breast cancer recurrence or a new breast cancer malignancy, compared with 7.7 percent or 17 women in the control arm.

The estimated 5-year cumulative rate for disease recurrence was 22.2 percent for the HRT arm and 9.5 percent in the control arm, for an absolute increase in risk of 14.2 percent.

"The results of the HABITS trial indicate a substantial risk for a new breast cancer event among breast cancer survivors using [HRT]. The risk elevation is in line with the evidence from observational studies and randomized trials that [HRT] increases the risk of breast cancer in healthy women," the authors write.

The findings were published online March 25 in the Journal of the National Cancer Institute.

Source: ANI
SRM/L
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Women and Cancer Breast Biopsy Pagets disease of the breast Mastitis Menopause Hot Flash Vaginitis Cancer and Homeopathy Endometrial Cancer Breast Cancer Facts 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive