6-months of growth hormone replacement therapy increased bone formation, bone marrow fat and muscle mass, vitamin
D level, thigh muscle mass while led to decrease in the abdominal fat in women with abdominal obesity, according to a study by the University of Alabama at Birmingham.
Due to obesity the growth hormone level in the body is reduced. This lower level of growth hormones makes obese women more prone to osteoporosis.
When scientists subjected about 79 women to growth hormone replacement therapy they noted that patients with the greatest abdominal fat loss had the greatest increases in bone formation.
Also, patients with the greatest increases in vitamin D had the greatest
increases in bone formation. Women with maximum abdominal fat loss had greater increases in bone formation.
The results of this study suggest new treatment possibilities for obesity-related bone loss. But high cost of growth hormone replacement therapy can limit its widespread use.
The research was presented at the annual meeting of the Radiological Society of North America (RSNA).