J. Alzheimers Dis. 2020 Jan 28
Relationship of Established Cardiovascular Risk Factors and Peripheral Biomarkers on Cognitive Function in Adults at Risk of Cognitive Deterioration.
Lai MMY, Sharman MJ, Ames DJ, Ellis KA, Cox KL, Hepworth G, Desmond P, Cyarto EV, Martins RN, Masters CL, Lautenschlager NT
There is a paucity of information on the role of microvascular and inflammatory biomarkers in cognitive dysfunction. ...
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Source: PubMed
Neuroimage 2020 Jan 30
Identifying a task-invariant cognitive reserve network using task potency.
van Loenhoud AC, Habeck C, van der Flier WM, Ossenkoppele R, Stern Y
Cognitive reserve (CR) is thought to protect against the consequence of age- or disease-related structural brain changes across multiple cognitive dom ...
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Source: PubMed
Forensic Sci Int Genet
The evaluation of seven age-related CpGs for forensic purpose in blood from Chinese Han population.
Pan C, Yi S, Xiao C, Huang Y, Chen X, Huang D
Age prediction of biological samples is one of the important tasks in forensic DNA phenotyping, and DNA methylation is regarded as the most promising ...
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Source: PubMed
Aging Clin Exp Res 2020 Jan 31
Driving status and health-related quality of life among the oldest old: a population-based examination using data from the AgeCoDe-AgeQualiDe prospective cohort study.
Hajek A, Brettschneider C, Lühmann D, van den Bussche H, Wiese B, Mamone S, Weyerer S, Werle J, Leve V, Fuchs A, Röhr S, Stein J, Bickel H, Mösch E, Heser K, Wagner M, Scherer M, Maier W, Riedel-Heller SG, Pentzek M, König HH
It is almost unknown whether the driving status is associated with HRQOL among individuals in highest age. ...
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Source: PubMed
Sci Rep
Nox2 dependent redox-regulation of microglial response to amyloid-ß stimulation and microgliosis in aging.
Geng L, Fan LM, Liu F, Smith C, Li J-
Microglia express constitutively a Nox2 enzyme that is involved in neuroinflammation by the generation of reactive oxygen species (ROS). Amyloid ß (Aß ...
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Source: PubMed
