Cell. Mol. Life Sci. 2020 Feb 01
EMT signaling: potential contribution of CRISPR/Cas gene editing.
Mohammadinejad R, Biagioni A, Arunkumar G, Shapiro R, Chang KC, Sedeeq M, Taiyab A, Hashemabadi M, Pardakhty A, Mandegary A, Thiery JP, Aref AR, Azimi I
Epithelial to mesenchymal transition (EMT) is a complex plastic and reversible cellular process that has critical roles in diverse physiological and p ...
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Source: PubMed
Brief. Bioinformatics 2020 Feb 02
Domain-specific introduction to machine learning terminology, pitfalls and opportunities in CRISPR-based gene editing.
O'Brien AR, Burgio G, Bauer DC
The use of machine learning (ML) has become prevalent in the genome engineering space, with applications ranging from predicting target site efficienc ...
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Source: PubMed
Metab. Eng. 2020 Jan 30
A genetic toolbox for metabolic engineering of Issatchenkia orientalis.
Cao M, Fatma Z, Song X, Hsieh PH, Tran VG, Lyon WL, Sayadi M, Shao Z, Yoshikuni Y, Zhao H
The nonconventional yeast Issatchenkia orientalis can grow under highly acidic conditions and has been explored for production of various organic acid ...
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Source: PubMed
DNA Repair (Amst.)
Drosophila Xrcc2 regulates DNA double-strand repair in somatic cells.
Bayer FE, Deichsel S, Mahl P, Nagel AC
Genomic integrity is challenged by endo- and exogenous assaults that are combated by highly conserved DNA repair mechanisms. Repair of DNA double-stra ...
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Source: PubMed
Metab. Eng. 2020 Jan 29
CRISPR/Cas9 directed editing of lycopene epsilon-cyclase modulates metabolic flux for ß-carotene biosynthesis in banana fruit.
Kaur N, Alok A, Shivani, Kumar P, Kaur N, Awasthi P, Chaturvedi S, Pandey P, Pandey A, Pandey AK, Tiwari S
Banana is one of the most economically important fruit crops worldwide. Genetic improvement in banana is a challenging task due to its parthenocarpic ...
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Source: PubMed
