About My Health Careers Internship MedBlogs Contact us
Medindia
LOGIN REGISTER
Advertisement

Thiazides found To Decrease the Risk of Fractures In Alzheimer's

by Ramya Rachamanti on April 24, 2019 at 6:24 PM
Font : A-A+

Thiazides found To Decrease the Risk of Fractures In Alzheimer's

Thiazide diuretics usage was associated with reduced risk of low energy fractures among Alzheimer's disease patients, according to a new study from the University of Eastern Finland, published in Osteoporosis International.

The association was found in long-term use exceeding three years; however, shorter term use did not reduce the risk of fractures. Thiazides are typically prescribed to treat hypertension.

Advertisement


Hip fracture was the most common low energy fracture in the study population, and the risk of this fracture type decreased by 30% in long-term thiazide use. The association may be related to the fact that thiazides decrease urinary calcium excretion and increase bone mineral density, which may decrease the risk of fracture in case of a fall.

Persons with Alzheimer's disease have an increased risk of falling, as the disease leads to problems in balance and spatial orientation.

The association of thiazide use and a reduced risk of low energy fractures disappeared in approximately one month after the use was discontinued. Thiazides are used in the treatment of hypertension.
Advertisement

In this study, thiazide use was taken into account also when these drugs were combined with other antihypertensive drugs in the same tablet. Thiazides cannot be recommended for the prevention of fractures, as their use is known to be associated with postural hypotension and consequent falls.

The study was based on the nationwide register-based MEDALZ study conducted at the University of Eastern Finland. For this study, 10,416 community-dwelling persons diagnosed with Alzheimer's disease who had a low energy fracture were included and compared with 31,099 matched controls without a fracture.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Emotional Healing
Psychosis Risk Related to Cat Parasite
Sedentary Behavior Precipitates Night-Time Hot Flashes
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Fracture of Knee Cap Osteoporosis Benefits of Blood Pressure Tablets on your Health Stress Fracture Compound Fractures 

Recommended Reading
Effect of Antihypertensive Medications on Fracture Risk
A research study examined the effects of antihypertensive medications on the incidence of pelvic ......
Benefits of Blood Pressure Tablets on your Health
Hypertension affects about a billion individuals worldwide and is a silent killer. Medication & life...
Compound Fractures
Compound Fracture is an injury that occurs when a fracture directly communicates with the external e...
Fracture of Knee Cap
Patella fracture is a kneecap injury that needs surgical correction. Undisplaced fracture can be hea...
Osteoporosis
Osteoporosis is a bone disease that leads to an increased risk of fractures. The bone mass is reduce...
Stress Fracture
Stress fractures are small fractures which often occur in the weight bearing bones of the lower leg ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use