They've got the routine down pat and figure they'll be changing about 300 diapers and preparing about 168 bottles a week.
All while chasing after three others who are a few months shy of their fourth birthdays.
"You take what God gives you... and this is what he's decided we can handle," said Victoria Lasita, 39, who defied mind-boggling odds and delivered her second set of triplets Wednesday.
The news that the couple conceived both sets without the aid of fertility treatment, which significantly increases the chances of a multiple pregnancy, shocked local fertility doctors.
"Holy smokes. Do you know what the odds of that are?" Glen Hofmann, medical director of the Bethesda Center for Reproductive Health and Fertility, told the Cincinnati Enquirer.
Since the odds of a woman having triplets naturally are about one in 8,000, the chances of having them twice are about one in 64 million, he said.
Casey Alexander was the first born at 1:57 pm Wednesday at just four pounds, 2.5 ounces. Seconds later, Caden Bradley was born at 4 pounds, 13.5 ounces and Carson Charles emerged two minutes later at four pounds, 9.5 ounces.
"Everybody seems to be doing well," 48-year-old father Tim, who witnessed the Caesarean-section birth in a delivery room brimming with 18 medical personnel, told the paper.
Tim was not sure when the babies will be ready to go home and join their older siblings, Jessica, Jillian and Brian.
The Lastians have been married six years and have three grown children from previous marriages. But they decided they'd like "one more" after the birth of the triplets.
"I guess we should have been more specific and said one more child, not one more set," Victoria said.