Erectile Dysfunction Drugs can Now Treat Various Other Conditions

by Hannah Joy on  April 21, 2018 at 2:26 PM Drug News
RSS Email Print This Page Comment bookmark
Font : A-A+

Drugs used to treat erectile dysfunction such as phosphodiesterase-5 (PDE5) inhibitors were also found to have clinical uses for a wide variety of conditions, reveals a new study.
Erectile Dysfunction Drugs can Now Treat Various Other Conditions
Erectile Dysfunction Drugs can Now Treat Various Other Conditions

PDE5 inhibitors cause blood vessel dilation by targeting a particular cellular pathway that is involved in many normal physiological functions and in the pathophysiology of a wide range of diseases.

PDE5 inhibitors likely have effects on many organs and functions, and they have been approved to treat lower urinary tract symptoms and pulmonary arterial hypertension. They are also being used off-label to treat conditions including diabetes and cancer.

The study was published in the British Journal of Pharmacology.

What is Erectile Dysfunction?

Erectile dysfunction, or ED, is a physical condition in males in which it is hard to achieve or maintain an erection firm enough for sex. It is also known as impotence.

When a man is sexually excited (aroused), his brain sends signals to the nerves in the penis. This leads to increased blood flow to the penis, causing the penis to expand and harden. Hence, anything which interferes with the nervous system or blood circulation could lead to erectile dysfunction.

Problems with erections occur in most men; however, when this happens very frequently, it is a sign of ED. It is a very common condition, especially in older men.

Oral medications:

Most cases of ED respond to oral medications. These medications enhance the effects of nitric oxide, a natural chemical the body produces that relaxes blood vessels in the penis. This, in turn, increases blood flow to the penis and leads to an erection, in response to sexual stimulation.

These oral medications are known as phosphodiesterase-5 (PDE-5) inhibitors and include the following:
  • Sildenafil
  • Tadalafil
  • Vardenafil
  • Avanafil
  • These are prescription drugs approved by FDA and are successful in generating an erection sufficient for intercourse in about 70 percent of men.

    The effects of these ED drugs may vary to quite an extent from person to person. They do not exhibit a strong response in men suffering from diabetes, heart disease and with damaged nerves or arteries.



    Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

More News on:

Drugs In Impotence Drug Toxicity Erectile Dysfunction Priapism Andropause / Male Menopause Premature Ejaculation Drugs Causing Sexual Problems Drugs Banned in India Peyronie´s Disease Drugs for Erectile Dysfunction 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive