About My Health Careers Internship MedBlogs Contact us

Erectile Dysfunction Drugs can Now Treat Various Other Conditions

by Hannah Joy on April 21, 2018 at 2:26 PM
Font : A-A+

Erectile Dysfunction Drugs can Now Treat Various Other Conditions

Drugs used to treat erectile dysfunction such as phosphodiesterase-5 (PDE5) inhibitors were also found to have clinical uses for a wide variety of conditions, reveals a new study.

PDE5 inhibitors cause blood vessel dilation by targeting a particular cellular pathway that is involved in many normal physiological functions and in the pathophysiology of a wide range of diseases.

PDE5 inhibitors likely have effects on many organs and functions, and they have been approved to treat lower urinary tract symptoms and pulmonary arterial hypertension. They are also being used off-label to treat conditions including diabetes and cancer.

The study was published in the British Journal of Pharmacology.

What is Erectile Dysfunction?

Erectile dysfunction, or ED, is a physical condition in males in which it is hard to achieve or maintain an erection firm enough for sex. It is also known as impotence.

When a man is sexually excited (aroused), his brain sends signals to the nerves in the penis. This leads to increased blood flow to the penis, causing the penis to expand and harden. Hence, anything which interferes with the nervous system or blood circulation could lead to erectile dysfunction.

Problems with erections occur in most men; however, when this happens very frequently, it is a sign of ED. It is a very common condition, especially in older men.

Oral medications:

Most cases of ED respond to oral medications. These medications enhance the effects of nitric oxide, a natural chemical the body produces that relaxes blood vessels in the penis. This, in turn, increases blood flow to the penis and leads to an erection, in response to sexual stimulation.

These oral medications are known as phosphodiesterase-5 (PDE-5) inhibitors and include the following:
  • Sildenafil
  • Tadalafil
  • Vardenafil
  • Avanafil
  • These are prescription drugs approved by FDA and are successful in generating an erection sufficient for intercourse in about 70 percent of men.

    The effects of these ED drugs may vary to quite an extent from person to person. They do not exhibit a strong response in men suffering from diabetes, heart disease and with damaged nerves or arteries.

    Source: Eurekalert

News A-Z
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drugs In Impotence Drug Toxicity Erectile Dysfunction Priapism Andropause / Male Menopause Premature Ejaculation Drugs Causing Sexual Problems Drugs Banned in India Peyronie´s Disease Drugs for Erectile Dysfunction 

Recommended Reading
Drugs In Impotence
Encyclopedia section of medindia gives information about the Impotence...
Andropause / Male Menopause
Andropause or male menopause causing low libido in a man is due to decreasing level of male hormones...
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Drugs Banned in India
Several drugs are either banned or withdrawn after introduction in the market....
Drugs Causing Sexual Problems
Sexual problems occur in males as well as in females. Drugs affecting the nervous and our endocrine...
Peyronie´s Disease
Peyronie''s disease is caused by scar tissue along the length of the penis, which causes the penis t...
Premature Ejaculation
Premature ejaculation is ejaculation that occurs before either of the partners is ready for it....
Priapism is persistent painful erection that lasts for more than four hours and is unrelated to sexu...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use