Levormeloxifene
Go to source), an enhanced 90's contraceptive 'Saheli' with minimal chemicals has been unveiled by the CSIR-Central Drug Research Institute (CDRI) in Lucknow. The breakthrough contraceptive is notably more effective to the human body with its reduced dose and chemical burden compared to existing market options. Once a staple during the 1990s, Saheli, also known as 'Chaya' under the National Family Planning programme, has now evolved into Levormeloxifene.
Development of Levormeloxifene as a Targeted Contraceptive
Radha Rangarajan, Director of CSIR-CDRI, explained, "The core objective behind this contraceptive's development was to minimize the chemical content, particularly crucial for women in their reproductive phase who predominantly consume such tablets." Rangarajan elaborated, "The compound ormeloxifene within Saheli comprises two enantiomers, dextro-ormeloxifene, and levo-ormeloxifene (levormeloxifene). Extensive preclinical studies have indicated higher efficacy of the levo counterpart, levormeloxifene. This research solely focuses on testing the levo model as a contraceptive, thereby reducing the unnecessary use of dextro-ormeloxifene and alleviating women from undue chemical exposure."
Birth Control Patch
A birth control patch is a new method of contraception for women for once weekly external application and contains both estrogen and progesterone.
A birth control patch is a new method of contraception for women for once weekly external application and contains both estrogen and progesterone.
‘Levormeloxifene, developed by CDRI, is an updated iteration of the 1990s 'Saheli' contraceptive pill. #BirthControlPills #Contraceptives’
Tweet it Now
The development of this groundbreaking contraceptive is the culmination of a decade-long intensive research effort led by a team of scientists, including Wahajul Haq, Vivek Bhosle, Arun Trivedi, Rajesh Jha, Rabi Bhatta, Sharad Sharma, SK Rath and others. Upon successful clinical trials, this contraceptive will bolster family planning initiatives, adding to the existing range of contraceptive services within the programme. Notably, Cipla has received approval from the Drugs Controller General of India to conduct Phase-I clinical trials for Levormeoxifene. (2✔ ✔Trusted Source
Recommendations of the SEC meeting to examine IND proposals
Go to source) This investigational drug is a collaborative effort between Cipla and CSIR-CDRI, Lucknow, aimed at developing an oral, non-hormonal contraceptive solution.
References:
- Levormeloxifene - (https://pubchem.ncbi.nlm.nih.gov/compound/35805)
- Recommendations of the SEC meeting to examine IND proposals - (https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadCommitteeFiles/Minutes%20of%20IND%20Committee%20meeting%20held%20on%2005.06.2023.pdf)
Birth Control Pills
Oral contraceptive or birth control pills contain hormones that prevent pregnancy. It is one of the most reliable methods of contraception.
Oral contraceptive or birth control pills contain hormones that prevent pregnancy. It is one of the most reliable methods of contraception.
Birth Control Pills to Delay Periods
Thinking of delaying your period with birth control pills? First, you should know all the benefits and risks. Find out more about your options here.
Thinking of delaying your period with birth control pills? First, you should know all the benefits and risks. Find out more about your options here.
Test Your Knowledge on Birth Control Pills
Birth control pills are daily pills that contain hormones to control and change the body’s functions to prevent pregnancy. Its main function is to prevent the release of an egg during the monthly menstrual cycle. It also works on the mucus lining ...
Birth control pills are daily pills that contain hormones to control and change the body’s functions to prevent pregnancy. Its main function is to prevent the release of an egg during the monthly menstrual cycle. It also works on the mucus lining ...
