Aspirin Therapy may Not Help Women Undergoing IVF to Conceive

by Medindia Content Team on October 24, 2007 at 6:18 PM
Aspirin Therapy may Not Help Women Undergoing IVF to Conceive

A systematic review of nine studies has shown that women undergoing in vitro fertilization (IVF) cannot rely upon low-dose aspirin to increase their chances of having a successful pregnancy.

Earlier studies have shown that aspirin therapy improves pregnancy rates for women undergoing IVF, while others have indicated that it increases the risk of miscarriage.


"It is thought by some that taking low-dose aspirin may improve blood flow to the uterus and therefore improve ovarian response to IVF treatment, so it may be of benefit to women who have previously responded poorly to IVF treatment," said the review's lead author Vanessa Poustie, Ph.D., at the Institute for Child Health at the University of Liverpool in England.

In the current review, Poustie and colleagues examined data from 1,449 women undergoing in vitro fertilization or intracytoplasmic sperm injection (ICSI) to treat infertility.

The studies compared the pregnancy and birth rates of women taking low-dose aspirin (150 milligrams or less taken once per day) to women taking a placebo or no treatment. Two of the studies took place in the United States; other studies were conducted in Hong Kong, Iran and Finland.

According to the review results, women taking aspirin while undergoing IVF or ICSI were not significantly more likely to become pregnant than women taking a placebo or no treatment.

In addition, no considerable difference in live birth rates existed between the treatment and control groups, according to the two studies that examined this outcome.

"Despite a number of high-profile studies, there still remains insufficient evidence to be able to say whether low-dose aspirin can increase the chance of women undergoing IVF having a successful pregnancy," Poustie said.

One of the largest studies included in the review found that 45 percent of the women taking aspirin became pregnant, compared with 28 percent of the women in the control group; however, the data were not strong enough to recommend this treatment routinely to women on IVF, the reviewers said.

"Further research would need to be undertaken before we can say whether the use of low-dose aspirin has a beneficial or detrimental effect on women undergoing IVF," Poustie said. Although in agreement with the study authors that further research into this treatment is needed, Randall Hines, M.D., director of the division of reproductive endocrinology and infertility at the University of Mississippi Medical Center, said that a number of IVF programs already use low-dose aspirin and it would be risky to change current practice based on the available data.

"Low-dose ASA may help some patients and does not appear to do harm," Hines said.

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research.

Source: ANI
Font : A-A+



Recommended Readings

Latest Women Health News

Persistent Health Issues for 1 in 3 New Mothers Post Childbirth
More than a third of women worldwide encounter persistent health concerns, such as depression, lower back pain, and various childbirth-related conditions.
Could Zinc Be the New Solution for Vaginal Yeast Infections?
New findings lead to advancements in treating vaginal yeast infections by offering fresh insights into how microbes within the body absorb zinc.
AI Tool Precisely Detects Postpartum Hemorrhage
An AI tool called Flan-T5 identified postpartum hemorrhage with 95% precision and detected 47% patients with the condition.
Active Scrutiny of Cervical Lesions Fuels Long-Term Cervical Cancer Risk
Active surveillance of cervical lesions was associated with higher cervical cancer risk in the long term compared to its removal.
Contraceptive Pills To Go Over-the-Counter Sale in Japan
Japan initiated the trial of selling morning-after contraceptive tablets over-the-counter in an effort to lower abortion rates and solace for rape victims.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Aspirin Therapy may Not Help Women Undergoing IVF to Conceive Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests