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More than Seventy Percent of Top US Hospitals Control Patient Temperature with High-Tech Arctic Sun(TM)

Tuesday, March 11, 2008 General News
LOUISVILLE, Colo., March 10 Led by the nation's tophospitals, adoption of the safest, most effective cooling technology-the non-invasive Arctic Sun(R)-is increasing rapidly. The number of top hospitalsinducing hypothermia and then rewarming their critically ill patients with theArctic Sun rose to more than 72 percent in 2007 from 60 percent the previousyear.

Thirteen of the 18 top-ranked U.S. News & World Report hospitals (72.2percent); 16 of the top 20 heart programs (80 percent); and 16 of the top 20neurology programs cool and rewarm patients with Medivance's precise, automatedhigh-tech Arctic Sun device.

"Fever kills brain cells. This notion that 'temperature is brain' hasbecome a key concept used in the management of patients in our NeuroICU , saysDr. Andrew Kofke, Co-Director of Neurocritical Care at the Hospital of theUniversity of Pennsylvania, which is ranked among the nation's best overallhospitals. "I believe state -of-the-art temperature management, using devicessuch at the Arctic Sun cooling system, combined with pharmacological aids, isan essential element in prevention of secondary brain damage after a braininjury."

A growing body of clinical data published in the New England Journal ofMedicine and other top-tier journals indicates that lowering body temperatureto therapeutic levels, followed by slow rewarming, limits neurologic damage ina wide range of critically ill patients.

"Adoption of the Arctic Sun by the vast majority of the nation's tophospitals demonstrates that its the best temperature management systemavailable today and validates our premise that safe, non-invasive coolingcoupled with the ability to rewarm slowly and precisely holds great promise inimproving patient outcomes," says Medivance CEO Robert Kline.

The Arctic Sun transfers up to five times more energy than conventionalproducts such as water blankets, wraps or ice packs. Its ArcticGel(TM) padscool rapidly, the result of direct thermal conduction between circulating waterand a patient's skin.

The number of teaching and community hospitals that cool with the ArcticSun is also growing rapidly due to its ease of use, speed with which nurses caninitiate the therapy, and the far greater safety of technologically advancedsurface cooling. Non-invasive temperature control does not put patients atunnecessary risk of deep vein thrombosis (DVT), bleeding or infectionassociated with invasive devices.

Cooling a standard of care

In 2005, the American Heart Association (AHA) issued recommendations andguidelines for inducing mild hypothermia in comatose survivors of cardiacarrest, making cooling a standard of care.

About Medivance's Arctic Sun

The non-invasive Arctic Sun Temperature Management System preciselymonitors and maintains core body temperature in a therapeutic range, between320 and 38.50 Celsius (approximately 89.60 to 101.30 Fahrenheit) with thepotential to minimize damage to the heart and brain. The Arctic Sun hasreceived 510 (k) FDA clearance in the U.S., the European Union's CE Mark, andmarketing approval in Japan. Medivance develops and manufactures non-invasive,proprietary therapeutic temperature management solutions. More information atwww.medivance.com.

SOURCE Medivance
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