Pluripotent Stem Cells

Pluripotent Stem Cells

• During cell division, the number of stem cells increases, but the number of different cell types produced are limited. After 5 days of division hollow ball of blastocyst cells are formed.
• The outer blastocyst cell layer forms the placenta that provides nourishment to the fetus.

• Pluripotent embryonic stem cells ( ES cells) are formed from the inner group of stem cells and help in formation of the embryo's tissues.
• Pluripotent cells are more versatile than an adult stem cell and can produce many different cell types.
• These cells are easier for controlling growth and differentiation than adult stem cells.
• Pluripotent stem cells are more abundant than adult stem cells and therefore significantly easier to isolate.
• Research studies done on animal ES cell (Pluripotent embryonic stem cells) experiments can be used to understand Human stem cells.

Human pluripotent stem cells can be produced from:

• Isolation of ES cells from blastocyst during in vitro fertilization.
• ES cells can be extracted from eggs or sperms of aborted or miscarried fetus.
• Production of tailor made ES cells from patients own differentiated cells by using cloning techniques.

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