Cardiac Marker genes

'Cardiac marker genes are thought to participate in cardiomyocyte differentiation and to contribute to heart hypertrophy in animal models', says the results published in Cardiovasc Pathol.2007 Nov-Dec;16(6):329-35. Epub 2007 Jun 20.


Early cardiac marker genes include: cardiac-specific homeobox (Csx/Nkx2.5), myocardin, homeodomain only protein, GATA4, and myocyte enhancer factor 2C. Altered expressions of early cardiac marker genes and differentiation-specific marker genes have been found in patients with the condition called hypertrophic cardiomyopathy.

References:

1. Cecil Medicine, 23rd Ed. Harrison's PRINCIPLES OF INTERNAL MEDICINE, 17^TH Edition
2. Cardiovasc Pathol. 2007 Nov-Dec;16(6):329-35. Epub 2007 Jun 20.
3. INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH Volume 29, Number 2, 56-63, DOI: 10.1007/s005990050064

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