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Health Canada Approves BAVENCIO™ (Avelumab for Injection) for the Treatment of Metastatic Merkel Cell Carcinoma (MCC) in Previously Treated Adult Patients

Thursday, February 22, 2018 Cancer News
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BAVENCIO™ Product Monograph. December 18, 2017.

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Fitzgerald T., et al. Dramatic Increase in the Incidence and Mortality from Merkel Cell Carcinoma in the United States. The American Journal of Surgery. 2015: 81(8): 802-806.

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Statistics Canada. Population by year, by province and territory. Available at: http://www.statcan.gc.ca/tables-tableaux/sum-som/l01/cst01/demo02a-eng.htm Accessed December 2017.

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Allen PJ., Bowne W., Jaques D., et al. Merkel cell carcinoma: prognosis and treatment of patients from a single institution. Journal of Clin Oncology. 2005;23(10):2300-2309.

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Andea A., Coit D., Amin B., et al. Merkel cell carcinoma: histologic features and prognosis. Cancer 2008;113(9):2549-2558.

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Andea A., Patel R., Ponnazhagan S., et al. Merkel cell carcinoma: correlation of KIT expression with survival and evaluation of KIT gene mutational status. Human Pathology. 2010;41(10):1405-1412.

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Santamaria-Barria J., Boland G., Yeap B., et al. Merkel cell carcinoma: 30-year experience from a single institution. Annals of Surgical Oncology. 2013;20(4):1365-1373.

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Stokes JB, Graw KS, Denel LT, et al. Patients with Merkel cell carcinoma tumors < or = 1.0 cm in diameter are unlikely to harbor regional lymphnode metastasis. Journal of Clinical Oncology. 2009;27(23):3772-3777.

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