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Xceed Molecular Launches Ziplex(R) Automated Gene-Expression System at the Association for Molecular Pathology, Booth 84/85

Wednesday, November 7, 2007 General News
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WELLESLEY, Mass., Nov. 7 Xceed Molecular, a pioneer in thedevelopment of cost-effective, easy-to-use gene-expression analysis systems,announced that the company will launch its Ziplex Automated Gene-ExpressionSystem for research use only at the Association for Molecular Pathology (AMP)Annual Meeting and Exhibit, which opens today at the Hyatt Regency CenturyPlaza Hotel in Los Angeles. The first integrated system designed for automatedgene-expression analysis, the Ziplex System comprises an automatedworkstation, TipChip consumable arrays, and reagents.
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Xceed designed the Ziplex System to make routine molecular diagnosticsboth feasible and affordable. "The routine clinical laboratory will require asystem that is reliable and easy to operate," said Xceed's President and CEO,David Deems. "As a fully automated and integrated platform, the Ziplex Systemis unmatched for both its ease-of-use and reliability of results, deliveringsuperior accuracy, reproducibility, speed, and scalability at significantlylower cost than conventional array- or PCR-based systems. The Ziplex Systemallows researchers to perform testing at approximately one-third the cost andin one-third the time of conventional platforms. After the sample preparationhas been completed, the hands-on time to process eight samples isapproximately 20 minutes. We believe our System will help make the promise ofpersonalized medicine a reality."
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While today is the official launch of the Ziplex System, biomedicalresearchers across the country are already familiar with the system'sperformance, according to Deems. The company has been offering ExpressionServices for the last year, and has presented data at a number of importantconferences. Deems continued, "Xceed is developing a pipeline of diagnosticassays for use on the Ziplex System. There is a great deal of interest infocused content - and there are few competitive alternatives. We expect tohave a variety of condition- or pathway-specific Signature Chips that will beavailable both as catalog products and through Xceed's Expression Services.The Metabolic Signature Chip, designed to investigate differential expressionassociated with diseases of the metabolic system (e.g. muscle disorders,obesity, and other metabolic diseases), is available today. In addition, Xceednow offers the Breast and Colon Cancer Signature Chips. We have a number ofother Signature Chips in development for inflammation and for a range ofcancers, including prostate, lung, and melanoma. We are actively pursuinglicensing arrangements with strategic partners to add other signatures to ourpipeline."

The list price for the Ziplex Automated Workstation, which automates thehybridization, imaging, quantitation, and quality control, is $85,000 USD. TheTipChip consumable that contains assay-specific content can cost as little as$120 USD per TipChip. (The price will vary based on content.) As part of theAMP launch, Xceed is offering special promotional pricing for early adopters.

Technical Topics Workshop

Xceed is also sponsoring a Technical Topics Workshop at the conference:Translational Research of Gene-Expression Assays to the Ziplex AutomatedWorkstation by David Englert, PhD. Time: 1 to 2 pm, Wed, Nov 7, 2007, HyattRegency Century Plaza Hotel Constellation Room A.

About Xceed Molecular

Xceed's vision is to advance molecular diagnostics by successfullytranslating novel multiplex tests into routine clinical practice and to createrobust diagnostic solutions to improve disease outcomes. Our products comprisethe Ziplex(R) System for automated gene-expression analysis (available in theUS and Canada for research use only), gene expression services, and pre-configured arrays. Xceed is also developing multiplexed genomic tests for theZiplex platform, both internally and with strategic partners. Xceed's R&D andmanufacturing are headquartered in Toronto, Ontari
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