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Waters Unveils Significant Advances in Mass Spectrometry and Separations Science, Helping Laboratories Accelerate Discovery, Efficiency and Productivity

Monday, June 2, 2008 General News J E 4
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DENVER, June 2 Waters Corporation (NYSE: WAT)today unveiled several new mass spectrometry innovations at the 56th AmericanSociety for Mass Spectrometry Conference on Mass Spectrometry and AlliedTopics, including the Waters(R) Xevo(TM) TQ MS System, an advanced tandemquadrupole mass spectrometer that allows scientists with varying levels ofmass spectrometry (MS) expertise to quickly produce the highest quality datawith confidence.

In addition, Waters is previewing its new TRIZAIC(TM) UPLC(R) System withnanoTile(TM) technology, a new UltraPerformance LC(TM) separations platformfor both large- and small-molecule applications that will deliverinformation-rich, high-sensitivity analyses when coupled to Waters SYNAPT(TM)High Definition MS(TM) (HDMS(TM)) and SYNAPT MS Systems. Other productsannounced include the VERIFYE(TM) High Definition Proteomics System, thenanoACQUITY UPLC(R) System with 2D Technology, and the Atmospheric SolidsAnalysis Probe (ASAP(R)).

"Mass spectrometry is a vital analytical tool for a wide variety ofapplications -- pharmaceuticals, biotechnology, food safety, environmental,"said Art Caputo, Executive Vice President and President of the Waters Division."Waters is meeting customers' needs by bringing to market technology thatallows laboratories to be more efficient and productive and makeshigh-performance capabilities available to scientists in various disciplines."

Xevo TQ MS - Making High-End MS Performance More Accessible

The Xevo TQ MS System introduced today is an advanced tandem quadrupolemass spectrometer designed to deliver unrivalled performance and functionality.It uses innovative IntelliStart(TM) and ScanWave(TM) technologies to deliverversatility and advanced quantitative capability to a broader range ofscientists. IntelliStart is new technology that simplifies instrument setupand time-intensive troubleshooting. It automatically ensures the system isready for use by performing mass calibration, setting MS resolution,generating compound-specific MS methods (SIR or MRM) and optimizing API sourceconditions for specific analytical conditions plus much more.

The Xevo TQ MS System operating under MassLynx(TM) Software is equippedwith a unique collision cell that can be operated in conventionalT-Wave(TM)(1)-enabled mode or in a new ScanWave-enabled mode. The ScanWave isan innovative use of T-Wave collision cell technology that improves duty cycleand significantly enhances the full scan capability to meet the demands oftoday's complex analyses. This allows scientists to more easily confirm theidentities and structures of targeted analytes.

A New Separations Platform for Proteomics Research

Also at ASMS, Waters is previewing its new TRIZAIC UPLC System withnanoTile Technology. The first iteration of this innovation is the new TRIZAICUPLC System with nanoTile Technology designed to deliver exceptionalsensitivity for limited-sample, direct-flow, nanoscale protein separations.For use with Waters SYNAPT HDMS and SYNAPT MS Systems, it combines novelmicrofluidic separation technology with Waters sub-two-micron columnchemistries, unique solvent delivery and comprehensive data management forboth large- and small-molecule applications. TRIZAIC represents ahighly-intelligent, integrated systems approach to separation science --fueled by the company's unequalled UPLC technology.

"TRIZAIC is a way for us to take the complexity out of characterizingproteins using nanoscale chromatographic separations. This proprietarytechnology is directed at those scientists who are looking for the enhancedresolution that direct-nanoflow UPLC brings to protein characterization,sensitivity and reproducibility," said Dr. Patricia Young, Senior ProductMarketing Manager, Waters Division. "We expect this platform willsignificantly streamline the process of reproducibly identifying andcharacterizing proteins."

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