SANTA CRUZ, Calif., Nov. 29, 2016 /PRNewswire/ -- SomaGenics, an RNA-focused biotechnology company, announced expansion ofits intellectual property portfolio with issue of two new patents for its RNA analysis technologies (miR-ID® and RealSeq®) and European patent protection for its therapeutic short synthetic hairpin RNA (sshRNA) agents.
The second issued continuation (U.S. 9,493,818) broadens coverage of SomaGenics' RealSeq® platform that enables the preparation of small RNA sequencing libraries with dramatically reduced incorporation bias. RealSeq®'s distinctive feature is a single combo-adaptor molecule that ligates to RNA ends more efficiently than other adapter designs. Both RealSeq® and miR-ID® are also protected by international patents. "The discovery rate and anticipated clinical utility of miRNAs and their isomiRs and isoforms is steadily increasing. For the development of miRNAs as biomarkers, sensitive and unbiased detection by next-generation sequencing and accurate qPCR validation are essential," explained Dr. Brian Johnston, CEO/President of SomaGenics.
SomaGenics' sshRNA® RNA interference technology received coverage in Europe with the grant of European Patent No. EP 2,352,744. The patented sshRNAs are distinct from conventional short hairpin RNAs in that they interact directly with Argonaute-2 (Ago-2) without prior processing by Dicer. This feature avoids off-target effects. Notably, sshRNAs have also been shown to have outstanding potency and pharmacokinetic properties without undesirable immune stimulation. In the US this technology is protected by Patent Nos. US 8,283,460 and US 8,779,115. It encompasses the design of SomaGenics' therapeutic candidates in the areas of chronic wound healing and viral infections.
"We are excited by the opportunities this expanded patent protection affords. SomaGenics is actively seeking partners for further development or licensing," said Johnston.
SomaGenics is a privately held biotech company with offices and laboratories located in Santa Cruz, Calif. It specializes in developing innovative technologies that focus on RNA molecules as therapeutic agents and targets as well as biomarkers. Besides miR-ID®, miR-Direct® and the Real-Seq® family, the company's detection technology platform also includes res-Q®, a method for quantifying fragmented RNA from formaldehyde-fixed, paraffin-embedded histology specimens. SomaGenics's therapeutics platform includes development of targets for its proprietary small short hairpin RNA (sshRNA) in wound healing and anti-viral applications.
Website: www.somagenics.comContact: Anne Scholz, 831 426 7700 x 20.
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SOURCE SomaGenics, Inc.
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