Disadvantage of the test is the presence of circulatory antigen for many days even after elimination of viable parasite.
This test is still being established.
Detection of specific parasite Nucleic acids done by Polymerase Chain Reaction (
This technique is more accurate and reliable than Microscopic techniques
But the test is very expensive and requires highly equipped laboratory.
Drug Resistance Tests:
Drug resistance tests are performed to evaluate the efficacy of the drug against the malarial parasite mostly in an invitro technique.
In vitro tests: The Minimum concentration of the drug required to inhibit the growth of the parasite in a culture medium is detected by this method.
In vitro Molecular detection:
- Molecular tests done to evaluate the degree of resistance to drugs
- Molecular markers assessed by PCR or Gene Sequencing.