About
Whipple’s disease is a serious
Whipple’s disease is caused as a reaction to an infection with a bacterium called Tropheryma whippelii.
The predominant symptoms of Whipple’s disease are due to the involvement of the digestive tract and the subsequent malabsorption of nutrients. Other systems like the joints and the brain are also commonly involved.
The reverse transcriptase PCR test, done on biopsy samples of affected tissues, helps in the definitive diagnosis of the condition.
Antibiotics like trimethoprim-sulphamethoxazole are effective in the treatment of Whipple’s disease, to which a dramatic response is often observed. Treatment has to be continued over prolonged durations.
References:
- Ratnaike RN. Whipple’s disease. Postgrad Med J 2000;76:760–766
- Fenollar F, Raoult D. Clinical and Diagnostic Laboratory Immunology 2001;8: 1-8.
Latest Publications and Research on Whipple’s Disease
- Corrigendum to 'Whipple's endocarditis diagnosed by thrombus analysis retrieved by successful mechanical thrombectomy' [Journal of the Neurological Sciences 400 (2019) 42-43]. - Published by PubMed
- Thrombocytopenia and endocarditis in a patient with Whipple's disease: case report. - Published by PubMed
- Pathologic Complete Response of Pancreatic Cancer following Neoadjuvant FOLFIRINOX Treatment in Hepatic Metastasized Pancreatic Cancer. - Published by PubMed
- Corrigendum to 'Whipple's endocarditis diagnosed by thrombus analysis retrieved by successful mechanical thrombectomy' [Journal of the Neurological Sciences 400 (2019) 42-43]. - Published by PubMed
- Chronic bursitis and tenosynovitis revealing Whipple's disease. - Published by PubMed
Citations
Please use one of the following formats to cite this article in your essay, paper or report:
-
APA
Dr. Simi Paknikar. (2013, April 26). Whipple’s Disease - Symptoms - Signs - Diagnosis - Treatment - Reference. Medindia. Retrieved on Jun 28, 2022 from https://www.medindia.net/patients/patientinfo/whipples-disease.htm.
-
MLA
Dr. Simi Paknikar. "Whipple’s Disease - Symptoms - Signs - Diagnosis - Treatment - Reference". Medindia. Jun 28, 2022. <https://www.medindia.net/patients/patientinfo/whipples-disease.htm>.
Chicago
Dr. Simi Paknikar. "Whipple’s Disease - Symptoms - Signs - Diagnosis - Treatment - Reference". Medindia. https://www.medindia.net/patients/patientinfo/whipples-disease.htm. (accessed Jun 28, 2022).
Harvard
Dr. Simi Paknikar. 2021. Whipple’s Disease - Symptoms - Signs - Diagnosis - Treatment - Reference. Medindia, viewed Jun 28, 2022, https://www.medindia.net/patients/patientinfo/whipples-disease.htm.