What is the Prognosis of Aarskog–Scott Syndrome?
Some children with Aarskog–Scott syndrome are born with serious heart defects. Some males suffer reduced fertility.
People with Aarskog–Scott syndrome may have a mild degree of mental slowness. Affected children usually have good social skills. Reduced fertility is a problem faced by some of the affected males.
- Changes in the brain
- Testes may fail to descend (cryptorchidism)
- Poor alignment of teeth
- Some children are born with serious heart defects. Cleft lip with or without an opening in the roof of the mouth (cleft palate) is also found in some.
- Aarskog D (1970). "A familial syndrome of short stature associated with facial dysplasia and genital anomalies". J. Pediatr. 77 (5): 856–61
- Scott CI (1971). "Unusual facies, joint hypermobility, genital anomaly and short stature: a new dysmorphic syndrome". Birth Defects Orig. Artic. Ser. 7 (6): 240–6.
- Orrico A, Galli L, Buoni S, Hayek G, Luchetti A, Lorenzini S, Zappella M, Pomponi MG, Sorrentino V. Attention-deficit/hyperactivity disorder (ADHD) and variable clinical expression of Aarskog-Scott syndrome due to a novel FGD1 gene mutation (R408Q). Am J Med Genet A. 2005 May 15;135(1):99-102.
- A.D.A.M, U.S. National Library of Medicine, Wikepedia