What are the Effects of Teratogenic Drugs on the Fetus?Teratogenic drugs can cause birth defects including cleft lip, cleft palate, and organ deformities. Effects of some common teratogenic drugs are listed below-Tetracyclines- Discolored and deformed teeth, retarded bone growthIsoretinoin- Craniofacial, heart and brain defectsNSAIDS- Premature closure of ductus arteriosusAnti-cancer drugs- Cleft palate, underdevelopment, mental retardation; or fetal deathAnti-seizure medications- Spina bifida, organ deformities, cleft palate, and facial defects Androgens- Masculization of the female fetusLithium- Fetal goitre, cardiac and other abnormalitiesThalidomide- Phocomelia (short or absent long bones of the limbs), multiple birth defectsWarfarin- Nose, eye and hand defects; growth retardation Published on Sep 23, 2014Last Updated on Apr 22, 2016