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Fetal Developement

Last Updated on Apr 22, 2016
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What are the Effects of Teratogenic Drugs on the Fetus?

Teratogenic drugs can cause birth defects including cleft lip, cleft palate, and organ deformities.

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Effects of some common teratogenic drugs are listed below-

  • Tetracyclines- Discolored and deformed teeth, retarded bone growth
  • Isoretinoin- Craniofacial, heart and brain defects
  • NSAIDS- Premature closure of ductus arteriosus
  • Anti-cancer drugs- Cleft palate, underdevelopment, mental retardation; or fetal death
  • Anti-seizure medications- Spina bifida, organ deformities, cleft palate, and facial defects
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  • Androgens- Masculization of the female fetus
  • Lithium- Fetal goitre, cardiac and other abnormalities
  • Thalidomide- Phocomelia (short or absent long bones of the limbs), multiple birth defects
  • Warfarin- Nose, eye and hand defects; growth retardation

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