These medicines help regulate weight either by altering appetite, increasing the rate of metabolism or inhibiting absorption from the digestive tract.
Common side-effects include high blood pressure, palpitations, restlessness and insomnia. Long-term use of weight loss drugs can cause addiction and tolerance. Also, the use of most diet pills in combination with each other has not been well studied.
Weight loss drugs are not a cure-all for obesity. Their use should be combined with exercise and improved diet to lose and maintain weight successfully over long term.
Reference for Weight Loss Drugs
- Coutinho W. The first decade of sibutramine and orlistat: a reappraisal of their expanding roles in the treatment of obesity and associated conditions. Arq Bras Endocrinol Metab. 2009;53/2: 262-70.
- Tziomalos K, Krassas G, Tzotzas T. The use of sibutramine in the management of obesity and related disorders: An update. Vascular Health and Risk Management 2009:5 441–452
- Leite C, Mocelin CA, Petersen GO, Leal MB, Thiesen FV. Rimonabant: an antagonist drug of the endocannabinoid system for the treatment of obesity. Pharmacological Reports 2009, 61:217-224
- Questions and Answers about FDA’s Initiative Against Contaminated Weight Loss Products- (http://www.fda.gov/Drugs/ResourcesForYou/Consumers/QuestionsAnswers/ucm136187.htm)
Latest Publications and Research on Weight Loss Drugs
- The effect of gabapentin and pregabalin on bone turnover and bone strength: A prospective study in Wistar rats. - Published by PubMed
- Anti-Obesity Effects of Grateloupia elliptica, a Red Seaweed, in Mice with High-Fat Diet-Induced Obesity via Suppression of Adipogenic Factors in White Adipose Tissue and Increased Thermogenic Factors in Brown Adipose Tissue. - Published by PubMed
- 5-year mental health and eating pattern outcomes following bariatric surgery in adolescents: a prospective cohort study. - Published by PubMed
- Sleep Apnea, Obesity, and Disturbed Glucose Homeostasis: Epidemiologic Evidence, Biologic Insights, and Therapeutic Strategies. - Published by PubMed
- Micro-RNA and the Features of Metabolic Syndrome: A Narrative Review. - Published by PubMed