A thorough physical check up may indicate meningoencephalitis, swelling of the brain and meninges.
Blood tests are done to gauge albumin levels, ESR count and Globulin in the
- To check the presence of motile trypanosomes, it is necessary to conduct a microscopic investigation of the blood, bone marrow and the cerebrospinal fluid. The chancre fluid and lymph node aspirates are also screened to verify the presence of infection causing agents.
- Mini anion-exchange/centrifugation and the quantitative buffy coat (QBC) are effective concentration techniques, mandatory to be conducted before the commencement of microscopic inquiry.
- In chagas disease blood samples are used to develop a culture of the infecting parasite.
- Xenodiagnosis, is a strategy of feeding the uninfected reduvid bugs with human blood. After a month elapses, the bug’s gut is clinically checked for the presence of parasites.
- A series of immunodiagnostic tests such as, radioimmunoassay complement fixation, indirect fluorescent assay, ELISA, PCR, indirect hemagglutination are employed to identify the strains of Trypanosoma cruizi amidst conflicting pathogenecities.
- Chagas Disease - (http://www.nlm.nih.gov/medlineplus/chagasdisease.html)