“Shaped like a butterfly she sits within the neck,” that’s what an anonymous poet wrote about the thyroid gland. but it can become cancerous and spread to other areas of the body, hence early diagnosis of the symptoms, its risk factor are important for the success of its treatment.
Thyroid cancer has become more common in recent years, and is one of the commonest types of cancers that arise in the endocrine system. An individual of any age group can be affected, thus even children less than 10 years may become victims. Women are three times at a higher risk to get the cancer.
Surveys have discovered "a belt of thyroid cancer" in women in coastal districts of Kerala, Karnataka, and Goa.
The cancerous cells pile up forming a growth or tumour. In the case of a thyroid, the preferred term for this growth is ‘nodule.’
Nodules can be benign (meaning ‘not a cancer’) or malignant (meaning ‘cancer’)
Fortunately 90 percent of thyroid nodules are benign. That is they rarely pose threat to life, don’t spread to other parts of the body, and do not usually need to be removed. This is not the case when it comes to ‘malignancy.’ Intervention is called for when a nodule is branded malignant.
Cancer cells are naughty students that never restrict themselves to their allotted seats. They run about. The spread is referred to as ‘metastasis.’ They travel through blood vessels, lymph vessels (tubes that carry lymph and white blood cells) to other parts of the body.
The lymph nodes (rounded masses of tissues located along the lymph vessels), lungs and bones are the favourite destinations for the cancer cells of thyroid.
A thyroid cancer cell that has reached a bone or lung behaves just like a ‘thyroid cancer’ and not a bone or lung cancer. It is hence called a metastatic cancer.
ANATOMY AND PHYSIOLOGY The thyroid is a gland at the front of your neck beneath your voice box (Larynx). A healthy thyroid usually cannot be felt through the skin. The 25-30gm weighing butterfly has two wings called lobes connected by an isthmus.
The thyroid is a vital member that affects the heart rate, blood pressure, body temperature, and weight. To do these, the gland secretes a hormone (a chemical) called Thyroxin. The thyroid follicular cells are responsible are the chef masters producing it. In addition there are C cells in the thyroid which makes another hormone called Calcitonin. It plays a tiny role in the maintenance of healthy Calcium levels in the body (the major players are the four Parathyroid glands located on the surface, behind the thyroid).
Just like any other organ, the thyroid is made up of tissues, which in turn are made up of the building blocks called cells. The lifecycle of a cell is usually systematic. A perfect harmony is usually in play. There are times though when chaos arise. Things go wrong, cells multiply at abnormal rates, and old cells turn reluctant to imbibe death. Thus walks in cancer, the deadly crab.
- Sabiston Textbook Of Surgery 18th Edition
- The follicular cancer lady: A must read article where the narrator describes her own experiences being a thyroid cancer patient. Hilarious to the core, perhaps the first of its kind write up. It is highly informative: The legend
- Famous thyroid cancer survivors: Catherine Bell
- New modalities of treatment like ‘alcohol ablation’ are being tried out at Mayo Clinic - (http://www.mayoclinic.org/thyroid-cancer/treatment.html)
Latest Publications and Research on Thyroid Cancer
- SEOM clinical guideline thyroid cancer (2019). - Published by PubMed
- Resibufogenin suppresses tumor growth and Warburg effect through regulating miR-143-3p/HK2 axis in breast cancer. - Published by PubMed
- FAM83D promotes epithelial-mesenchymal transition, invasion and cisplatin resistance through regulating the AKT/mTOR pathway in non-small-cell lung cancer. - Published by PubMed
- SLC34A2 simultaneously promotes papillary thyroid carcinoma growth and invasion through distinct mechanisms. - Published by PubMed
- Preoperative Voice Characteristics in Thyroid Patients. - Published by PubMed