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Lambert-eaton Syndrome

Written by Himabindhu
Medically Reviewed by The Medindia Medical Review Team on Apr 03, 2015
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Other Names :  

Lambert–Eaton myasthenic syndrome, Eaton–Lambert syndrome

What is Lambert-eaton Syndrome ?  

Lambert-eaton Syndrome is a rare autoimmune disorder involving the muscles of the limbs. The muscles become weak due to problems in the neuromuscular junctions.


Cause(s) :  
  • Lambert-Eaton syndrome is often associated with lung cancer.
Symptoms :  
  • Limb muscles closest to the trunk become weak, difficulty in climbing stairs and raising from sitting position.
  • Weakness of mouth and throat muscles
  • Weakness of eye muscles - double vision, drooping of eyelids, swallowing difficulty
Disruption of the autonomic nervous system:
  • Dry mouth
  • Constipation
  • Blurred vision
  • Impaired sweating
  • Drop in blood pressure on standing
Diagnosis and Tests :  
  • EMG
  • CT
  • PET
Specialist to consult :  Neurology

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