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Rheumatoid Arthritis

Last Updated on Jul 28, 2021
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What is Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints and the surrounding tissues. It is an autoimmune disease.

Rheumatoid Arthritis

Rheumatoid arthritis can occur at any age, but is more common in middle age. Women are more prone to the disease than men.

The exact cause of rheumatoid arthritis is unknown. Infection, genes and hormonal changes may be linked to the disease.

Rheumatoid arthritis leads to pain, swelling, stiffness and loss of function in the joints. Being a systemic disease, it tends to affect other organs in the body as well.

Rheumatoid arthritis progresses in 3 stages:

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  • Stage 1- Swelling of the synovial lining; causing pain, warmth, stiffness, redness and swelling around the joint.
  • Stage 2- Rapid division and growth of cells, or pannus; which causes the synovium to thicken.
  • Stage 3- The inflamed cells release enzymes that might damage bone and cartilage; often causing the involved joint to lose its shape and alignment, causing more pain and loss of movement.

As there is no specific laboratory test to diagnose rheumatoid arthritis, the diagnosis is based on patient’s medical history and physical examination. The rheumatoid factor (RF) is found in the blood and synovial fluid of 80% of people with rheumatoid arthritis and can aid in diagnosis.

Rheumatoid arthritis requires lifelong treatment with medications, physical therapy, exercise, education and surgery. Early, aggressive treatment can delay joint destruction.

What is New in Rheumatoid arthritis?

1. When Arthritis Flares Up, Drug Infused Hydrogel Will Become Responsive

Anti-inflammatory drug loaded hydrogel started releasing the drug when the inflammation was triggered by arthritis-related enzymes which usually occurs in patients with arthritis, finds a new study. The findings of this study are published in the journal of APL Bioengineering. The drug-loaded hydrogel is designed in such a way that drug release is triggered by the activity of arthritis-related enzymes that are increased during arthritis flare episodes and when it is more severe, the locally injected hydrogel degrades more rapidly corresponding to increased effective drug release.

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Latest Publications and Research on Rheumatoid Arthritis


Do you wish to consult a Rheumatologist for your problem? Ask your question

Dr. Santhosh Babu M R
Dr. Santhosh Babu M R
MBBS, DPhysMed
37 years experience
Apollo Sugar Clinic, Patturaikkal, Thrissur
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Comments

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tigersue51

Hi what is the generic pill for methotrexate?

kiel888

I have RA,and the causes are the food I eat,when I work so hard and tired and then accidentally. i washed my hands with cold water.

Don't eat all kinds of beans, peanuts, vegetables with high uric acid like cabbage and fish with so much blood...red meats...

raksha22

my name is raksha thaker I suffering from Rhematoid Artritis since ten years guide me

Diwata

I'm 39 yrs. old now, but I started feeling pain in my joints [knees and ankles] when I was very young. As I grow older, the swelling includes my fingers and wrest. When I was in college, my joints in ankles, knees, wrest and finger were inflamed. I can't even walk and use the toilet by myself. My parents could not send me to a doctor because medication is not included in the budget and is very expensive. When I start working, its my neck that is inflamed. Finally I had the chance to see a doctor. It was seen in my x-ray that I had spurs in my cervical spine 3,4 and 5, that's why my hands sometimes are weak and numb. 4 yrs ago, my doctor asked me to undergo MRI, but until now I did not do it because it cost a lot. thanks to this website, I learn more about my condition.

imranphysio99

why did u nt gone to rhematic department of kolkata medical college,one of the best hospital for rheumatism disease. imran

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