Reye’s syndrome, owing to its rarity is often misdiagnosed as encephalitis, meningitis, diabetes or poisoning. Diagnosis of Reye’s syndrome follows the elicitation of a proper medical history and detailed physical examination. No specific treatment exists. Children should be managed in an intensive-care unit.
Cause of Reye's Syndrome
The exact cause of Reye's syndrome is unknown. The disease may occur following a viral illness, particularly an upper respiratory tract infection (URTI), influenza, varicella (chicken pox), or gastroenteritis. Reye's syndrome is particularly associated with the use of aspirin in children with viral infections. Nimesulide is another drug that could cause Reye’s syndrome when used in similar situations. Adults may rarely suffer Reye’s syndrome even in the absence of aspirin usage. Drugs like paracetamol, outdated tetracycline, valproic acid, zidovudine, didanosine, and antiemetics are also associated with Reye's or Reye's-like syndrome. Inborn Errors of Metabolism (IEMs) produce Reye's-like syndromes.
Latest Publications and Research on Reye’s SyndromeDihydrolipoamide dehydrogenase deficiency: A still overlooked cause of recurrent acute liver failure and Reye-like syndrome. - Published by PubMed
Use of common migraine treatments in breast-feeding women: a summary of recommendations. - Published by PubMed
Cerebellar Mutism Caused by Primary Varicella Infection in an Immunocompetent Child. - Published by PubMed