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Renal Cell Carcinoma

Last Updated on May 14, 2018
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Renal cell carcinoma is kidney cancer that affects the lining of the kidney tubules. The initial stages of the cancer are asymptomatic in most patients and this makes early management of the disease difficult.

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Renal cell carcinoma accounts for about 3% of all adult cancers and is also the most common of kidney cancers (90-95%) affecting mostly men, between the ages 50-70 years.

Renal Cell Carcinoma / Kidney Cancer

Renal cell carcinoma is commonly seen to affect North Americans and those of Scandinavian ancestry more often than it affects people of Asian or African descent. In the United States, Blacks are more affected than the Whites. Also, the incidence in men is greater than that seen in women. Although the disease is usually detected after age 50, it is seen to occur in young people too who have a family predisposition.

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Renal cell carcinoma (RCC) is known for its lack of early symptoms and resistance to treatments such as chemo and radio therapy. However, of late, it has been noticed that these cancers are being detected early and managed through treatments such as thermal ablation, nephron –sparing surgeries, with radical nephrectomy (removal of the kidney and surrounding structures) being the gold standard in treating central and large tumors. Also, targeted therapy is being effectively applied in those with metastatic disease, where the cancer has spread to other parts of the body.

What is new in Renal Cell Carcinoma?

1. People With Kidney Cancer Could be at a Real Risk From NSAIDS

Ibuprofen and other non-steroidal anti-inflammatory medications apart from aspirin could decrease free survival time for patients with metastatic renal cell carcinoma (mRCC)- a type of renal cancer, finds a new study.

2. Improper Sleep may Negatively Impact People With Kidney Diseases

Improper sleep may affect patients with chronic kidney diseases, as their health-related quality of life (HRQOL) may get reduced in this process, finds a new study. An adequate amount of sleep is essential for homeostatic regulation (body's ability to control internal environment), while sometimes excess sleep has also been said to harm the Kidney disease patients by causing obesity, diabetes or hypertension.

References:

  1. Barjorin D. Tumors of the kidney, bladder, ureters, and renal pelvis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 2003.
  2. National Comprehensive Cancer Network. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Kidney Cancer. 2012. Version 1.2012.

Latest Publications and Research on Renal Cell Carcinoma

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