Last Updated on Dec 06, 2019


Pyloric stenosis is a rare disorder in adults that is caused due to abnormal thickening of pyloric sphincter muscle, thereby narrowing the gastric outlet.

Pyloric stenosis a rare digestive tract disorder in adults is caused due to the abnormal thickening of pyloric sphincter muscle. This is the muscle that surrounds the lower end of the stomach that leads to the intestines. Thus, in pyloric stenosis, the gastric outlet is narrowed and the passage of food into the intestines is obstructed.

Pyloric stenosis is more common in infants than in adults. This is usually a consequence of a congenital defect.

In most cases in adults, pyloric stenosis occurs as a result of chronic ulcers or fibrosis near the gastric outlet.(1)

Symptoms occur due to inability of the food to pass easily from the stomach into the intestines. The patient experiences projectile vomiting of partially digested food after eating; the vomitus does not contain bile. In addition the patient also complains of frequent pain in the upper part of the abdomen, early satiety, nausea, loss of appetite and weight loss. At times, non-projectile vomiting and jaundice may occur. Some of the symptoms resemble those of stomach cancer, which has to be ruled out in these patients.(2)

The condition is diagnosed using imaging studies and endoscopy. It is treated surgically.


  1. Pyloric Stenosis - (
  2. Idiopathic Hypertrophic Pyloric Stenosis in an Adult, a Potential Mimic of Gastric Carcinoma - (
  3. Everything You Should Know About Pyloric Stenosis - (
  4. Pyloric Stenosis - An Overview - (
  5. Adult Idiopathic Hypertrophic Pyloric Stenosis - (


Geoeaker Friday, November 16, 2018

Hello. Can Pyloric Stenosis reoccur? My husband had surgery for it when he was 2 weeks old. Has had some problems most of his life with indigestion and vomiting undigested food. It has become worse within the past year. Could it be reoccurring?

@Guest Wednesday, October 18, 2017

How large should your pyloric valve opening be in a small adult female? I just had mine balooned open during an endoscopy today and they said they need to do it again.

Barb555 Sunday, October 26, 2014

My son vomited as an infant, but outgrew it. At 22, he began to have problems with vomiting undigested foods. It happens about once a week now, and he cannot control it. It happens very quickly. He has had an endoscopy, and received a diagnosis of GERD. However the meds have not eliminated the problem. We have been to 2 different gastroenterologists. Should we go to another one?

razorgirl Thursday, October 22, 2015

No, because GERD can cause quick regurgitation of undigested food, especially when lying down. Ask about fundoplication surgery to treat it if meds aren't working.

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