Polycystic Ovarian Syndrome - Overview
Polycystic ovarian syndrome is the most common hormonal disorder among women of reproductive age and can cause infertility.
Polycystic ovary disease
Functional ovarian hyperandrogenism
Hyperandrogenic chronic anovulation
Ovarian dysmetabolic syndrome
Polycystic ovarian syndrome
Polycystic ovarian syndrome is the most common hormonal disorder among young women and a leading cause of infertility. Its exact cause is unknown.
"The physician should no longer regard these women as merely having annoying cosmetic complaints, or only suffering from infertility, but as having potential metabolic disorders that may be associated with type 2 diabetes and cardiovascular events," comments Rhoda H. Cobin, MD, FACE, Chair of the PCOS Task Force.
The syndrome was originally reported by Stein and Leventhal in 1935 when they described a group of women with absence of menstrual periods (amenorrhea), infertility, hirsutism (unwanted hair growth in women), and enlarged polycystic ovaries.
In this condition, the ovaries and adrenal glands produce more testosterone and less estrogen and progesterone than normal. This imbalance causes many of the symptoms of the disease.
Follicles of the ovary are the basic unit of female reproductive biology. They are usually round and contain a single egg (also called ovum). Normal ovarian volume in the menstruating females is 5-15 mL, with an approximate mean of 10 mL.
In polycystic ovary disease, the ovaries are enlarged, with a thick, scarred capsule associated with an abnormally high number of follicles in the ovaries. This gives the impression of multiple cysts and hence the term ‘polycystic’. Any ovarian follicle that is larger than two centimeters, is called an ovarian cyst. Cyst is a closed hollow sac that usually contain air, fluids, or semi-solid material.
The follicles in polycystic ovaries may concurrently exist in varying states of growth, maturation, or degeneration.
What is new in Polycystic Ovarian Syndrome / Polycystic ovary disease?
1. Liver Disease- Major Risk for Women With Polycystic Ovary SyndromeIncreasing level of male hormone which is responsible for polycystic ovary syndrome (PCOS) in women may also lead to non-alcoholic fatty liver disease, finds a new study. Women who have PCOS are two to three times more likely to develop the non-alcoholic fatty liver disease than women without PCOS.Read More..
- Current Perspectives in Polycystic Ovary Syndrome - (http://www.aafp.org/afp/20030815/697.html)
- Polycystic Ovary Syndrome: It's Not Just Infertility - (http://www.aafp.org/afp/20000901/1079.html)
- Imaging in Polycystic Ovary Disease - (http://www.emedicine.com/radio/topic565.htm)
Latest Publications and Research on Polycystic Ovarian SyndromeRole of Metformin on Osteoblast Differentiation in Type 2 Diabetes. - Published by PubMed
LncRNA HCP5 promotes cell proliferation and inhibits apoptosis via miR-27a-3p/IGF-1 axis in human granulosa-like tumor cell line KGN. - Published by PubMed
The effects of physical exercise on cardiometabolic outcomes in women with polycystic ovary syndrome not taking the oral contraceptive pill: a systematic review and meta-analysis. - Published by PubMed
Therapeutic potentials of the natural plant flavonoid apigenin in polycystic ovary syndrome in rat model: via modulation of pro-inflammatory cytokines and antioxidant activity. - Published by PubMed
Association between Dietary Glycaemic Index and Glycaemic Load and Adiposity Indices in Polycystic Ovary Syndrome. - Published by PubMed