Persistent Sexual Arousal Syndrome (PSAS) - Case Reports

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“The opening of the vagina is just as sensitive and a mere touch will bring me to orgasm. My husband is very sympathetic and relieves the terrible pressure anytime I ask.”

“My life has been sheer hell. I want my life back.”

“Sitting is unbearable, sometimes causing pressure to orgasm. Standing is the only time I feel nothing. Sitting in a car is torture.”

“I was constantly feeling overwhelming sensations of sexual arousal, which were purely physical and not accompanied by romantic or sexual fantasies.”

These are some of the anguished statements made by patients of Persistent Sexual Arousal Syndrome (PSAS) to their doctors and read out in medical forums to emphasize the need for research into this new challenge in women’s sexual health.

Dr. David Goldmeier who described PSAS in a report in the International Journal of STD and AIDS said women with PSAS who have sought treatment have reported extreme distress and even thoughts of suicide.

Considering the rarity with which this syndrome is reported by women it seems fitting to present two sample case reports from women interviewed by Dr. Sandra Leiblum and Dr. Sharon Nathan and reports gathered from obstetricians, gynecologists and other primary care doctors from other parts of the world who were presented with cases of PSAS.

Case Report 1: In 2001, a 52-year-old, divorced, working woman reported having Persistent Sexual Arousal Syndrome (PSAS) for 6 years and that it affected her work and destroyed her wellness. She reported persistent sensations of genital vascocongestion and masturbation offered no relief. With no thoughts of sex, her body would pulsate intensely with a constant need for release, sometimes with a reprieve only at sleep. She thought she was the only woman in the world with this peculiar problem and resorted to taking anti-depressants.

She was thoroughly examined by her family doctor, 3 gynecologists, a urologist, and a mental health specialist—and none of them could help her and had never heard of a distressing abnormality such as hers. The doctors were also baffled that her blood tests and hormone levels and an MRI scan showed normal. She said there was no history of psychological trauma. For six years she used anti-depressant drugs such as divalproex, sertraline, fluoxetine and buspirone that did not help her in any way. She said her sense of humor, support from family and friends helped ward off depression. With no forthcoming explanation or solution from doctors, the woman continues to suffer from PSAS.

Case Report 2: This is a case reported about a patient by a gynecologist in Australia. The patient is a 51-year-old woman with a “continual distressing feeling of sexual arousal.” The patient was unwilling to masturbate and orgasms did not relieve the persistent genital arousals. Androgen values and the results of abdominal computerized tomography covering the adrenal glands, lumbosacral spine and the pelvis were found to be normal. Neurologic findings were also normal. There was a mild tenderness in the suprapubic area. The patient reported using hormone replacement therapy for a few years for osteopenia and was not taking any alternative medicine therapy.

An endocrinologist in Phoenix, US, Dr. Randall Craig claims he has successfully treated two women with PSAS-like symptoms. In his letter posted on PSAS Support Group, he suggests that 3 hormones—progesterone, prolactin and oxytocin may play a role in PSAS. Particularly, women with insufficient oxytocin release after orgasm may experience PSAS symptoms. According to Dr. Craig inhaling oxytocin could relieve patients from symptoms of PSAS.

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I want to talk about this disorder I think i may have it I am a guy for years i dealt with feeling while i was trying to sleep of sexual touching which i thought was just normal for a while it progressed and eventually it became a daytime thing I would feel pleasure walking around doing my job with no erection which was weird because usually guys dont feel pleasure without and erection. I also have been told I have schitzofrenia and the voice at the time was calling it cbt or cognitive behavioral therapy they sometimes asked me if i wanted to feel it and always said yes the feelings responded to my conversation I was having with myself. I ended up in a mental hospital shortly after from hearing to much and responding to it by thinking that I have a chip in my brain from when i cracked it open and started thinking I was a test trial to some new science. I calmed down and started to try and rationalize it and decided that would not happen they gave me a medication for schitzofrenia which had a side effect of getting rid of my pleasure well mostly and have not felt touching or pleasure since then I didnt really talk alot with doctors about this because it was embarrassing.

Hello, Is there anyone that i can speak about this disorder? It is ruining my life. I need to talk someone who is PGAD. I will be waiting for your answer desperately.

hi i have pgad :) and i found that all i needed to make the discomfort go away was to get rid of my depression i found the right psych meds.. :) and i still get pgad but it feels great ps: my pelvis area is paralyzed i broke my lower spine and hip so i cant feel sex unless its the pgad

Hi. My name is April and I have suffered with PGAD for over two years. The horrible feeling of constant pain and arousal. I am 63 yrs. and this has ruined my life. Going somewhere , doing something, constant arousal..then the pain..I cried and took pain pills, which only helped a little. So so be so uncomfortable all the time, not even being able to go to the bathroom or shower. This is too much to bear. BUT this CAN. Yes CAN go away. It did for me and how? Sincerely And honestly pray. The power of prayer cured me. I prayed often, desperately , and and with faith. I am living proof that this works. Pray with your whole heart and soul. This will end in His time. It took a long time, but in His time it ended.. I promise you, it CAN. Go the Lord. Please don't get discouraged ...give it time and PRAY. I will pray for all of you too.

im 24 Years old, i have been dealing with this since I can remember, Probably since I hit Puberty. It is a nightmare, All day long i fight and fight the urge to go into the other room and take care of it, I fight because I know that it will only get worse. I finally got the courage to talk about it to my SO. He was amazing, and so understanding, and to be able to talk about it openly has relieved so much stress in my life. I can only hope that this disorder can get more attention, so that maybe one day I can live a normal life. Please, do not be afraid to talk about this to your partner, or your super close friend, challenge them to google ReGS, research it. Having someone to talk to, that understands what im going through has helped me in so many ways. I now have a daughter and its a struggle, but she has helped me fight my urges, and so has my SO.

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