Organophosphorus compounds or organophosphates are commonly used in the industrial, agricultural and home settings. They were initially developed as insecticides but some of them i.e. sarin, soman, tabun and VX have been developed as “nerve gases”. These are used as chemical warfare and in terrorist attacks.
Organophosphorus compounds are easily accessible and are often used to commit suicides. Accidental poisoning may also occur especially when they are kept within the reach of children. Farmers could get exposed while spraying crops if they are not well protected with masks, gloves and other protective clothing.
- Cherian MA, Roshini C, Peter JV, Cherian AM. Oximes in organophosphorus poisoning Indian Journal of Critical Care Medicine 2005 ; 9 (3): 155-163.
- Goodman and Gilman. The Pharmacological Basis of Therapeutics 11th edition.
Latest Publications and Research on Organophosphorus PoisoningPTEN/FLJ10540/PI3K/Akt cascade in experimental brain stem death: A newfound role for a classical tumorigenic signaling pathway. - Published by PubMed
Prolonged paralysis in a child with organophosphate pesticide poisoning. - Published by PubMed
Novichok agents: a historical, current, and toxicological perspective. - Published by PubMed
[Research progress in the mechaaism of lung injnry caused by aute organophosphorus compounds poisoning]. - Published by PubMed
[Analysis of pesticide poisoning in Ji'nan during 2012-2016]. - Published by PubMed