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Introduction - Metabolism & Metabolic Disorders
Metabolism is the sum total of all chemical and physical changes that take place in any organism that enables it to function and grow. It is nothing different from reactions taking place inside a chemistry laboratory. Just that it tends to happen in a more controlled way inside the body. The metabolic process is dependent on a number of factors such as enzymes and other chemical compounds for its completion. It can be represented as
Enzyme Y
↑
Substrate A→Product B→
Product C↓(Final end product)
Enzyme X
In a few cases, there is a block in any one of the steps of a reaction, either due to absence or deficiency of a particular enzyme. A disease arising out of such a defect is called a metabolic disorder.
Latest Publications and Research on Metabolic Defects
Retinal dysfunction parallels morphologic alterations and precede clinically detectable vascular alterations in Meriones shawi, a model of type 2 diabetes. - Published by PubMedThe Cut-off Values of Surrogate Measures for Insulin Sensitivity in a Healthy Population in Korea according to the Korean National Health and Nutrition Examination Survey (KNHANES) 2007-2010. - Published by PubMed
Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: a prospective cohort study. - Published by PubMed
Paternal uniparental disomy of chromosome 19 in a pair of monochorionic diamniotic twins with dysmorphic features and developmental delay. - Published by PubMed
Acute Neurologic Syndromes Beyond Stroke: The Role of Emergent MR Imaging. - Published by PubMed
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