Last Updated on Nov 20, 2018

Latest Publications and Research on Swine Flu

BMC Med Genomics    

HopPER: an adaptive model for probability estimation of influenza reassortment through host prediction.

Yin R, Zhou X, Rashid S, Kwoh CK

Influenza reassortment, a mechanism where influenza viruses exchange their RNA segments by co-infecting a single cell, has been implicated in several ... Read More

Source: PubMed


J. Virol.  2020 Jan 29  

A single amino acid at position 431 of the PB2 protein determines the virulence of H1N1 swine influenza viruses in mice.

Xu C, Xu B, Wu Y, Yang S, Jia Y, Liang W, Yang D, He L, Zhu W, Chen Y, Yang H, Yu B, Wang D, Qiao C

Genetic reassortments occurred continuously among multiple subtypes or genotypes of influenza viruses prevalent in pigs. Of note, some reassortant vir... Read More

Source: PubMed

Cold Spring Harb Perspect Med  2020 Jan 27  

Swine Influenza A Viruses and the Tangled Relationship with Humans.

Anderson TK, Chang J, Arendsee ZW, Venkatesh D, Souza CK, Kimble JB, Lewis NS, Davis CT, Vincent AL

Influenza A viruses (IAVs) are the causative agents of one of the most important viral respiratory diseases in pigs and humans. Human and swine IAV ar... Read More

Source: PubMed

J Assoc Physicians India    

Behavioral Patterns of Visitors Attending the Respiratory Diseases and Swine Flu OPD in Relation to Droplet Borne Infection: A Prospective Observational Study.

Galav V

... Read More

Source: PubMed

Emerging Infect. Dis.    

Interspecies Transmission of Reassortant Swine Influenza A Virus Containing Genes from Swine Influenza A(H1N1)pdm09 and A(H1N2) Viruses.

Everett HE, Nash B, Londt BZ, Kelly MD, Coward V, Nunez A, van Diemen PM, Brown IH, Brookes SM

Influenza A(H1N1)pdm09 (pH1N1) virus has become established in swine in the United Kingdom and currently co-circulates with previously enzootic swine ... Read More

Source: PubMed

Comments

om.rayhn Wednesday, August 15, 2012

This is an informative article on this subject and I really enjoyed the read. My regards and appreciation to the writer of this amazing material... To know more about Flu Symptoms

lillyadams790 Thursday, November 11, 2010

I am so worried about catching the swine flu. I have done everything in my power to protect myself and my family. Even to the point that if it were to become so out of control that we needed to be locked in our house for some time due to the pandemic.

DR_GGR_PEDIATRICIAN Thursday, August 12, 2010

Very good illustrations by Medindia.net. Dr.GANGADHAR RAO HYDERABAD

prema Wednesday, May 20, 2009

An interesting Abstract from a recent paper on Swine Flu

Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team

Background - On April 15 and April 17, 2009, novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from two epidemiologically unlinked patients in the United States. The same strain of the virus was identified in Mexico, Canada, and elsewhere. We describe 642 confirmed cases of human S-OIV infection identified from the rapidly evolving U.S. outbreak.

Methods - Enhanced surveillance was implemented in the United States for human infection with influenza A viruses that could not be subtyped. Specimens were sent to the Centers for Disease Control and Prevention for real-time reverse-transcriptase–polymerase-chain-reaction confirmatory testing for S-OIV.

Results- From April 15 through May 5, a total of 642 confirmed cases of S-OIV infection were identified in 41 states. The ages of patients ranged from 3 months to 81 years; 60% of patients were 18 years of age or younger. Of patients with available data, 18% had recently traveled to Mexico, and 16% were identified from school outbreaks of S-OIV infection.

The most common presenting symptoms were fever (94% of patients), cough (92%), and sore throat (66%); 25% of patients had diarrhea, and 25% had vomiting. Of the 399 patients for whom hospitalization status was known, 36 (9%) required hospitalization. Of 22 hospitalized patients with available data, 12 had characteristics that conferred an increased risk of severe seasonal influenza, 11 had pneumonia, 8 required admission to an intensive care unit, 4 had respiratory failure, and 2 died. The S-OIV was determined to have a unique genome composition that had not been identified previously.

Conclusions A novel swine-origin influenza A virus was identified as the cause of outbreaks of febrile respiratory infection ranging from self-limited to severe illness. It is likely that the number of confirmed cases underestimates the number of cases that have occurred.

Raja Ramachandran, Senior Resident Nephrology, PGIMER, Chandigarh,INDIA

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