Tissue Eng Regen Med  2020 Feb 01  

Primary Cilia Mediate Wnt5a/ß-catenin Signaling to Regulate Adipogenic Differentiation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Following Calcium Induction.

Bae YK, Kim GH, Kwon JH, Kim M, Choi SJ, Oh W, Um S, Jin HJ

Regeneration of soft tissue defects is essential for adipose tissue pathologies and disease, trauma, or injury-induced damage. Here, we show that umbi... Read More

Source: PubMed

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Sci Rep    

Repeated intramuscular transplantations of hUCB-MSCs improves motor function and survival in the SOD1 G93A mice through activation of AMPK.

Kook MG, Lee S, Shin N, Kong D, Kim DH, Kim MS, Kang HK, Choi SW, Kang KS

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is characterized by loss of motor neurons and degeneration of neuromuscu... Read More

Source: PubMed

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Transfus. Apher. Sci.  2020 Jan 27  

Effect of Cord Blood Platelet Gel on wound healing capacity of human Mesenchymal Stromal Cells.

Mallis P, Alevrogianni V, Sarri P, Velentzas AD, Stavropoulos-Giokas C, Michalopoulos E

Wound healing is a dynamic process, involving the recruitment of growth factors, cytokines, chemokines and cellular populations. Recently, the Cord Bl... Read More

Source: PubMed

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Cell Stem Cell  2020 Jan 27  

Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.

Hurley K, Ding J, Villacorta-Martin C, Herriges MJ, Jacob A, Vedaie M, Alysandratos KD, Sun YL, Lin C, Werder RB, Huang J, Wilson AA, Mithal A, Mostoslavsky G, Oglesby I, Caballero IS, Guttentag SH, Ahangari F, Kaminski N, Rodriguez-Fraticelli A, Camargo F, Bar-Joseph Z, Kotton DN

Alveolar epithelial type 2 cells (AEC2s) are the facultative progenitors responsible for maintaining lung alveoli throughout life but are difficult to... Read More

Source: PubMed

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Am. J. Physiol. Renal Physiol.  2020 Jan 31  

Soluble Fas affects erythropoiesis in vitro and acts as potential predictor of erythropoiesis-stimulating agents therapy in chronic kidney disease patients.

Chiloff DM, de Almeida DC, Dalboni MA, Canziani MEF, George SK, Morsi AM, El-Akabawy N, Porada CD, Durao MS, Zarjou A, Almeida-Porada G, Goes MA

Serum soluble Fas levels (sFas) is associated to erythropoietin (Epo) hyporesponsiveness in patients with chronic kidney disease (CKD). If sFas could ... Read More

Source: PubMed

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