27-hydroxycholesterol decreases cell proliferation in colon cancer cell lines.
Warns J, Marwarha G, Freking N, Ghribi O
Colorectal cancer (CRC) is the third most diagnosed cancer in the western world, affecting 1 out of approximately 22 people in their lifetime. Several... Read More
Can. J. Physiol. Pharmacol. 2018 Jul 16
Long-term atorvastatin treatment decreases heart maximal oxygen consumption and its vulnerability to in vitro oxidative stress in WHHL rabbit.
Tissier F, Farhat F, Philouze C, Desfontis JC, Didier R, Gilard M, Mallem MY, Mansourati J, Moisan C, PIchavant-Rafini K, Theron M, Amérand A
Statins are currently used in prevention of cardiovascular diseases in high risk populations, and could be considered in primary prevention. However, ... Read More
J Clin Epidemiol 2018 Jul 12
Using a single non-inferiority margin or preserved fraction for an entire pharmacological class was found to be inappropriate.
Althunian TA, de Boer A, Groenwold RHH, Klungel OH
To assess the impact on non-inferiority decisions when using a single margin or single preserved fraction (PF) for all non-inferiority trials within a... Read More
Chronic Use of Statins and Their Effect on Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.
Mahamid M, Watad A, Bragazzi NL, Wengrower D, Wolff J, Livovsky D, Amital H, Adawi M, Goldin E
Background and Aims: Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is one of the major complications of ERCP. Thus, se... Read More
J Biomed Res 2018 Jul 12
Pravastatin alleviates lipopolysaccharide-induced placental TLR4 over-activation and promotes uterine arteriole remodeling without impairing fetal development of rats.
Yang MY, Diao ZY, Wang ZY, Yan GJ, Zhao GF, Zheng MM, Dai A, Dai YM, Hu Y
Preeclampsia is associated with over-activation of the innate immune system in the placenta, in which toll-like receptor 4 (TLR4) plays an essential p... Read More