Shigellosis

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Latest Publications and Research on Shigellosis

J. Med. Microbiol.  2018 Jul 03  

Novel multiplex PCR assay for identification and subtyping of enteroinvasive Escherichia coli and differentiation from Shigella based on target genes selected by comparative genomics.

Dhakal R, Wang Q, Lan R, Howard P, Sintchenko V

Both Shigella and enteroinvasive Escherichia coli (EIEC) can cause enterocolitis, but they have a distinct epidemiology and public health relevance. C... Read More

Source: PubMed


Clin. Microbiol. Infect.  2018 Jun 28  

Update on vaccines for enteric pathogens.

Riddle MS, Chen WH, Kirkwood CD, MacLennan CA

Acute diarrheal disease caused by viral, bacterial and parasitic infections is a major global health problem with substantial mortality and morbidity ... Read More

Source: PubMed

Vaccine    

Cyclic OmpC peptidic epitope conjugated to tetanus toxoid as a potential vaccine candidate against shigellosis.

Jarzab A, Witkowska D, Ziomek E, Setner B, Czajkowska A, Dorot M, Szewczuk Z, Gamian A

In earlier works we have described that mice immunized with outer membrane protein OmpC survive the challenge with live Shigella flexnerii 3a. We have... Read More

Source: PubMed

J. Med. Microbiol.  2018 Jun 29  

Antimicrobial resistance profiles of Shigella dysenteriae isolated from travellers returning to the UK, 2004-2017.

Terry LM, Barker CR, Day MR, Greig DR, Dallman TJ, Jenkins C

Antimicrobial resistance (AMR) profiles of 754 strains of Shigella dysenteriae isolated between 2004 and 2017 from UK travellers reporting symptoms of... Read More

Source: PubMed

Chemistry    

Sugar Acetonides are a Superior Motif for Addressing the Large, Solvent-Exposed Ribose-33 Pocket of tRNA-Guanine Transglycosylase.

Movsisyan LD, Schäfer E, Nguyen A, Ehrmann FR, Schwab A, Rossolini T, Zimmerli D, Wagner B, Daff H, Heine A, Klebe G, Diederich F

The intestinal disease shigellosis caused by Shigella bacteria affects over 120 million people annually. There is an urgent demand for new drugs as re... Read More

Source: PubMed

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