Latest Publications and Research on Presbycusis

Redox Biol    

Redox activation of excitatory pathways in auditory neurons as mechanism of age-related hearing loss.

Rousset F, Nacher-Soler G, Coelho M, Ilmjarv S, Kokje VBC, Marteyn A, Cambet Y, Perny M, Roccio M, Jaquet V, Senn P, Krause KH

Age-related hearing (ARHL) loss affects a large part of the human population with a major impact on our aging societies. Yet, underlying mechanisms ar... Read More

Source: PubMed


Hear. Res.    

Generation of a ChATCre mouse line without the early onset hearing loss typical of the C57BL/6J strain.

Beebe NL, Sowick CS, Kristaponyte I, Galazyuk AV, Vetter DE, Cox BC, Schofield BR

The development of knockin mice with Cre recombinase expressed under the control of the promoter for choline acetyltransferase (ChAT) has allowed expe... Read More

Source: PubMed

Hear. Res.    

Age-related changes in the number of cresyl-violet-stained, parvalbumin and NMDAR 2B expressing neurons in the human spiral ganglion.

Kaur C, Saini S, Pal I, Kumar P, Chandra Sati H, Jacob TG, Bhardwaj DN, Roy TS

Animal-studies associate age-related hearing loss (presbycusis) with decreasing number of spiral ganglion neurons (SGNs) in Rosenthal's canal (RC) of ... Read More

Source: PubMed

Am J Geriatr Psychiatry  2020 Jan 14  

Subclinical Hearing Loss is Associated With Depressive Symptoms.

Golub JS, Brewster KK, Brickman AM, Ciarleglio AJ, Kim AH, Luchsinger JA, Rutherford BR

To assess whether the relationship between hearing and depressive symptoms is present among older adults classified as normal hearing (=25 dB).... Read More

Source: PubMed

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