Pract Radiat Oncol 2020 Jan 28
Erratum: A Case of Mistaken Identity: Paget's Disease of the Bone Causing Cord Compression-Case Report and Review of the Literature.
Browne C, Mutsaers A, Fisher B
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Source: PubMed
J. Bone Miner. Res. 2020 Jan 28
The loss of Profilin 1 causes early-onset Paget's disease of bone.
Scotto di Carlo F, Pazzaglia L, Esposito T, Gianfrancesco F
Paget's disease of bone (PDB) is a late-onset disorder frequently caused by mutations in the SQSTM1 gene, leading to hyperactive osteoclasts and resul ...
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Source: PubMed
Bone 2020 Jan 17
Pamidronate: A model compound of the pharmacology of nitrogen-containing bisphosphonates; A Leiden historical perspective.
Papapoulos SE
Pamidronate [3-amino-1-hydroxypropylidene-1,1-bisphosphonate (APD)] was the first nitrogen-containing bisphosphonate (N-BP) investigated in clinical s ...
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Source: PubMed
Fitoterapia
A review on osteoclast diseases and osteoclastogenesis inhibitors recently developed from natural resources.
Wang X, Yamauchi K, Mitsunaga T
Natural products have been investigated as potential candidates of novel therapeutics and play a crucial role in advanced medicinal drugs. Natural res ...
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Source: PubMed
Bone
Early-onset Paget's disease of bone in a Mexican family caused by a novel tandem duplication (77dup27) in TNFRSF11A that encodes RANK.
Iwamoto SJ, Rothman MS, Duan S, Baker JC, Mumm S, Whyte MP
Four heterozygous in-frame tandem duplications of different lengths in TNFRSF11A, the gene that encodes receptor activator of nuclear factor ?B (RANK) ...
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Source: PubMed
