Med. Hypotheses    

INAD and Duchenne muscular dystrophy, two ends of the iPLA2ß spectrum.

Offringa-Hup A

Infantile neuroaxonal dystrophy (INAD) and Duchenne muscular dystrophy (DMD) are two deadly neuromuscular degenerative diseases of childhood. Knowledg... Read More

Source: PubMed

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Ther Innov Regul Sci    

Updating the Clinical Picture of Facioscapulohumeral Muscular Dystrophy: Ramifications for Drug Development With Potential Solutions.

Huml RA, Uspenskaya-Cadoz O, Dawson J, Slifer Z

Facioscapulohumeral muscular dystrophy (FSHD) is a complex, inheritable, and rare muscle disease that affects the entire body. The major symptom of FS... Read More

Source: PubMed

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Skelet Muscle    

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators.

Lindsay A, Baumann CW, Rebbeck RT, Yuen SL, Southern WM, Hodges JS, Cornea RL, Thomas DD, Ervasti JM, Lowe DA

Dystrophin deficiency sensitizes skeletal muscle of mice to eccentric contraction (ECC)-induced strength loss. ECC protocols distinguish dystrophin-de... Read More

Source: PubMed

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Neuromuscul. Disord.  2019 Dec 17  

Clinical and genetic characterization of limb girdle muscular dystrophy R7 telethonin-related patients from three unrelated Chinese families.

Chen H, Xu G, Lin F, Jin M, Cai N, Qiu L, Ye Z, Wang L, Lin M, Wang N

Limb girdle muscular dystrophy LGMD R7 telethonin-related is a rare autosomal recessive muscle disorder characterized by proximal muscle weakness of p... Read More

Source: PubMed

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Plant Sci.    

Biotechnological, biomedical, and agronomical applications of plant protease inhibitors with high stability: A systematic review.

Cotabarren J, Lufrano D, Parisi MG, Obregón WD

Protease inhibitors (PIs) are regulatory proteins found in numerous animal tissues and fluids, plants, and microorganisms that reduce and inhibit the ... Read More

Source: PubMed

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