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Down Syndrome

Latest Publications and Research on Down Syndrome


Ir J Med Sci   2020 Jan 31   

A retrospective study of myeloid leukaemia in children with Down syndrome in Ireland.

Dowling GP, Piccin A, Gavin KT, Betts DR, Malone A, Cotter M, Sills A, Evans P, O' Marcaigh A, Smith OP

Acute megakaryoblastic leukaemia (AMKL) is a subtype of myeloid leukaemia and is the most common leukaemia type in children with Down syndrome (DS) un ... Read More

Source: PubMed
J Neurosurg Pediatr   2020 Jan 31   

Use of recombinant human bone morphogenetic protein for revision cervical spine fusion in children with Down syndrome: a case series.

Cohen LL, Yang BW, O'Neill NP, Proctor MR, Glotzbecker MP, Hedequist DJ

Patients with trisomy 21 (Down syndrome; DS) often have atlantoaxial instability (AAI), which, if severe, causes myelopathy and neurological deteriora ... Read More

Source: PubMed
Int J Surg Case Rep      

Posterior lumbar interbody fusion graft penetrated the lumbar thecal sac in a patient with rheumatoid arthritis: A case report.

Lim DJ, Lee JH

Intradural foreign bodies have been reported to be associated with disc material, tumors, and bullets following spinal gunshot injuries. In this repor ... Read More

Source: PubMed
Cancer Cell   2020 Jan 22   

THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells.

Sun C, Shou P, Du H, Hirabayashi K, Chen Y, Herring LE, Ahn S, Xu Y, Suzuki K, Li G, Tsahouridis O, Su L, Savoldo B, Dotti G

Chimeric antigen receptor (CAR) T cell costimulation mediated by CD28 and 4-1BB is essential for CAR-T cell-induced tumor regression. However, CD28 an ... Read More

Source: PubMed
Andrologia   2020 Jan 31   

A male Down syndrome with two normal boys: Cytogenetic, paternity and andrological investigations.

Jazayeri O, Gorjizadeh N

Down syndrome is the most common autosomal chromosome anomaly with several medical abnormalities and intellectual disability, occurring in about of 1: ... Read More

Source: PubMed
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