Int. Immunopharmacol.
Toll-like receptor 7 agonist imiquimod prevents the progression of SLE in MRL/lpr mice via inhibiting the differentiation of T follicular helper cells.
Duan X, Shen C, Zhang X, Wu L, Chen J, Ma B, Wang Q, Sun P, Lan Y, Su C
Previous research has recently indicated that TLR7 is able to induce CD4+T cell anergy, which is the opposite of the role it plays in innate immune ce ...
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Source: PubMed
Int. Immunopharmacol.
CTLA-4: From mechanism to autoimmune therapy.
Hosseini A, Gharibi T, Marofi F, Babaloo Z, Baradaran B
CD28 and CTLA-4 are both important stimulatory receptors for the regulation of T cell activation. Because receptors share common ligands, B7.1 and B7. ...
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Source: PubMed
Neuromuscul. Disord. 2019 Dec 14
Emerging therapies for autoimmune myasthenia gravis: Towards treatment without corticosteroids.
Tannemaat MR, Verschuuren JJGM
Myasthenia gravis is an autoimmune disease characterized by dysfunction of the neuromuscular junction. Current treatment is based on lifestyle advice, ...
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Source: PubMed
Mol. Immunol.
CD70-mediated CD27 expression downregulation contributed to the regulatory B10 cell impairment in rheumatoid arthritis.
Shi L, Hu F, Zhu L, Xu C, Zhu H, Li Y, Liu H, Li C, Liu N, Xu L, Mu R, Li Z
Regulatory B10 cells have been shown to exhibit impaired functions in autoimmune diseases. However, the underlying mechanism is still obscure. In the ...
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Source: PubMed
Comp. Immunol. Microbiol. Infect. Dis.
Emerging Involvement of long non-coding RNAs in gastrointestinal associated inflammatory disorders.
Lashgarian HE, Karkhane M, Marzban A, Yazdi M, Shahzamani K
Gastrointestinal (GI) disorders including a wide range of infectious, inflammatory, autoimmune, etc. disorders. Inflammatory bowel and celiac disease ...
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Source: PubMed
